BRD-A26032986_-666_MCF7_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
Similar Terms
Downloads & Tools

Genes

29 genes differentially expressed following the BRD-A26032986_-666_MCF7_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
AEBP1 AE binding protein 1
AMIGO2 adhesion molecule with Ig-like domain 2
CNPY3 canopy FGF signaling regulator 3
FABP7 fatty acid binding protein 7, brain
HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
INSIG1 insulin induced gene 1
LDLR low density lipoprotein receptor
PCSK1 proprotein convertase subtilisin/kexin type 1
PLK2 polo-like kinase 2
RCAN1 regulator of calcineurin 1
SCGB1D2 secretoglobin, family 1D, member 2
SCGB2A2 secretoglobin, family 2A, member 2
ST6GAL1 ST6 beta-galactosamide alpha-2,6-sialyltranferase 1
TFAP2A transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)
VTCN1 V-set domain containing T cell activation inhibitor 1

decreased expression

Symbol Name
APLP2 amyloid beta (A4) precursor-like protein 2
BAG3 BCL2-associated athanogene 3
CDC42EP3 CDC42 effector protein (Rho GTPase binding) 3
FERMT1 fermitin family member 1
HSPB8 heat shock 22kDa protein 8
ID1 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein
KCNJ15 potassium channel, inwardly rectifying subfamily J, member 15
STX1A syntaxin 1A (brain)
UBE2S ubiquitin-conjugating enzyme E2S
VCAN versican
WFDC2 WAP four-disulfide core domain 2
ZNF652 zinc finger protein 652