BRD-A25775766_-666_MCF7_24.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

76 genes differentially expressed following the BRD-A25775766_-666_MCF7_24.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCB6 ATP-binding cassette, sub-family B (MDR/TAP), member 6 (Langereis blood group)
ABCC3 ATP-binding cassette, sub-family C (CFTR/MRP), member 3
ABHD4 abhydrolase domain containing 4
AKR1B10 aldo-keto reductase family 1, member B10 (aldose reductase)
AKR1C1 aldo-keto reductase family 1, member C1
AKR1C2 aldo-keto reductase family 1, member C2
AKR1C3 aldo-keto reductase family 1, member C3
BAX BCL2-associated X protein
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CES1 carboxylesterase 1
CTSB cathepsin B
DUSP4 dual specificity phosphatase 4
DUSP5 dual specificity phosphatase 5
FOSL1 FOS-like antigen 1
FTH1 ferritin, heavy polypeptide 1
G6PD glucose-6-phosphate dehydrogenase
GCLM glutamate-cysteine ligase, modifier subunit
GDF15 growth differentiation factor 15
GPRC5A G protein-coupled receptor, class C, group 5, member A
GPX2 glutathione peroxidase 2
GULP1 GULP, engulfment adaptor PTB domain containing 1
HMOX1 heme oxygenase 1
IER3 immediate early response 3
IL13RA1 interleukin 13 receptor, alpha 1
ITGB5 integrin, beta 5
KIAA0368 KIAA0368
KYNU kynureninase
LRP10 low density lipoprotein receptor-related protein 10
MAFG v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog G
MAPKAPK2 mitogen-activated protein kinase-activated protein kinase 2
ME1 malic enzyme 1, NADP(+)-dependent, cytosolic
MICAL2 microtubule associated monooxygenase, calponin and LIM domain containing 2
NEBL nebulette
NEFL neurofilament, light polypeptide
NQO1 NAD(P)H dehydrogenase, quinone 1
NQO2 NAD(P)H dehydrogenase, quinone 2
OSMR oncostatin M receptor
RAP1GAP RAP1 GTPase activating protein
SESN1 sestrin 1
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
SMAD3 SMAD family member 3
SQSTM1 sequestosome 1
TRIM16 tripartite motif containing 16
TSKU tsukushi, small leucine rich proteoglycan
TXNRD1 thioredoxin reductase 1
UCHL1 ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)
UGDH UDP-glucose 6-dehydrogenase
ZMAT3 zinc finger, matrin-type 3

decreased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ACSL5 acyl-CoA synthetase long-chain family member 5
C4BPA complement component 4 binding protein, alpha
CNR1 cannabinoid receptor 1 (brain)
DLK1 delta-like 1 homolog (Drosophila)
FABP5 fatty acid binding protein 5 (psoriasis-associated)
GATM glycine amidinotransferase (L-arginine:glycine amidinotransferase)
GPM6A glycoprotein M6A
HEBP1 heme binding protein 1
HEY1 hes-related family bHLH transcription factor with YRPW motif 1
HLF hepatic leukemia factor
HNMT histamine N-methyltransferase
IGL immunoglobulin lambda locus
KRT23 keratin 23, type I
KRT5 keratin 5, type II
LOC100505650 uncharacterized LOC100505650
NFIB nuclear factor I/B
PKIG protein kinase (cAMP-dependent, catalytic) inhibitor gamma
TACSTD2 tumor-associated calcium signal transducer 2
TMEM14A transmembrane protein 14A
TNNT1 troponin T type 1 (skeletal, slow)
TPBG trophoblast glycoprotein
TPD52 tumor protein D52
TSC22D1 TSC22 domain family, member 1
TST thiosulfate sulfurtransferase (rhodanese)
TUBA1A tubulin, alpha 1a
VTCN1 V-set domain containing T cell activation inhibitor 1
ZBTB10 zinc finger and BTB domain containing 10