BRD-A25775766_-666_HT29_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
Similar Terms
Downloads & Tools

Genes

88 genes differentially expressed following the BRD-A25775766_-666_HT29_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AKR1B10 aldo-keto reductase family 1, member B10 (aldose reductase)
AKR1C1 aldo-keto reductase family 1, member C1
AKR1C2 aldo-keto reductase family 1, member C2
ALDH1A3 aldehyde dehydrogenase 1 family, member A3
BAG3 BCL2-associated athanogene 3
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
COMP cartilage oligomeric matrix protein
DNAJA1 DnaJ (Hsp40) homolog, subfamily A, member 1
DSP desmoplakin
ECM1 extracellular matrix protein 1
EZR ezrin
FLRT2 fibronectin leucine rich transmembrane protein 2
FOSL1 FOS-like antigen 1
GABPB1 GA binding protein transcription factor, beta subunit 1
GLS glutaminase
GPM6B glycoprotein M6B
GPRC5A G protein-coupled receptor, class C, group 5, member A
HMOX1 heme oxygenase 1
HSPA1A heat shock 70kDa protein 1A
HSPA8 heat shock 70kDa protein 8
IGFBP5 insulin-like growth factor binding protein 5
IGL immunoglobulin lambda locus
JUNB jun B proto-oncogene
KRT6B keratin 6B, type II
NPC1 Niemann-Pick disease, type C1
ODC1 ornithine decarboxylase 1
PBX3 pre-B-cell leukemia homeobox 3
PHACTR2 phosphatase and actin regulator 2
PHLDA1 pleckstrin homology-like domain, family A, member 1
POPDC3 popeye domain containing 3
RAD51C RAD51 paralog C
S100A7 S100 calcium binding protein A7
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
SQSTM1 sequestosome 1
TUBB2A tubulin, beta 2A class IIa
TXNRD1 thioredoxin reductase 1
UGDH UDP-glucose 6-dehydrogenase

decreased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ABLIM1 actin binding LIM protein 1
ADH1B alcohol dehydrogenase 1B (class I), beta polypeptide
ADIRF adipogenesis regulatory factor
AGTR1 angiotensin II receptor, type 1
ANXA4 annexin A4
B3GNT1
BCL6 B-cell CLL/lymphoma 6
CAMK2N1 calcium/calmodulin-dependent protein kinase II inhibitor 1
CHRDL1 chordin-like 1
CYFIP2 cytoplasmic FMR1 interacting protein 2
CYP3A5 cytochrome P450, family 3, subfamily A, polypeptide 5
DGKZ diacylglycerol kinase, zeta
DHRS2 dehydrogenase/reductase (SDR family) member 2
FBXO9 F-box protein 9
FGFR3 fibroblast growth factor receptor 3
FHL1 four and a half LIM domains 1
GATA2 GATA binding protein 2
GSDMB gasdermin B
GTF3A general transcription factor IIIA
HOPX HOP homeobox
HOXB7 homeobox B7
HSD17B11 hydroxysteroid (17-beta) dehydrogenase 11
IRS2 insulin receptor substrate 2
KRT7 keratin 7, type II
MAOA monoamine oxidase A
METTL7A methyltransferase like 7A
MMP7 matrix metallopeptidase 7
PDXK pyridoxal (pyridoxine, vitamin B6) kinase
PIK3C2B phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 beta
PPARG peroxisome proliferator-activated receptor gamma
PROM1 prominin 1
PRR15L proline rich 15-like
PRUNE2 prune homolog 2 (Drosophila)
PTGDS prostaglandin D2 synthase 21kDa (brain)
PTGER4 prostaglandin E receptor 4 (subtype EP4)
RAMP1 receptor (G protein-coupled) activity modifying protein 1
RGS2 regulator of G-protein signaling 2
RPS4Y1 ribosomal protein S4, Y-linked 1
SERPING1 serpin peptidase inhibitor, clade G (C1 inhibitor), member 1
SLC3A1 solute carrier family 3 (amino acid transporter heavy chain), member 1
SORL1 sortilin-related receptor, L(DLR class) A repeats containing
SPINK2 serine peptidase inhibitor, Kazal type 2 (acrosin-trypsin inhibitor)
SPON2 spondin 2, extracellular matrix protein
TCF4 transcription factor 4
TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)
TMEM123 transmembrane protein 123
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10
TRIB2 tribbles pseudokinase 2
TUBA4A tubulin, alpha 4a
UGT2B28 UDP glucuronosyltransferase 2 family, polypeptide B28