BRD-A25736793_everolimus_PC3_24_h_0.37_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

96 genes differentially expressed following the BRD-A25736793_everolimus_PC3_24_h_0.37_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ADGRG6 adhesion G protein-coupled receptor G6
AHR aryl hydrocarbon receptor
APOD apolipoprotein D
ATP2B1 ATPase, Ca++ transporting, plasma membrane 1
ATP9A ATPase, class II, type 9A
ATXN1 ataxin 1
BASP1 brain abundant, membrane attached signal protein 1
BHLHE41 basic helix-loop-helix family, member e41
CAMK2N1 calcium/calmodulin-dependent protein kinase II inhibitor 1
CDK19 cyclin-dependent kinase 19
CEACAM6 carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen)
CFD complement factor D (adipsin)
CREB1 cAMP responsive element binding protein 1
CTGF connective tissue growth factor
DUSP6 dual specificity phosphatase 6
DYNLT3 dynein, light chain, Tctex-type 3
EMP1 epithelial membrane protein 1
ENPP2 ectonucleotide pyrophosphatase/phosphodiesterase 2
EPAS1 endothelial PAS domain protein 1
F13A1 coagulation factor XIII, A1 polypeptide
FABP7 fatty acid binding protein 7, brain
FEZ1 fasciculation and elongation protein zeta 1 (zygin I)
FEZ2 fasciculation and elongation protein zeta 2 (zygin II)
FZD7 frizzled class receptor 7
GALC galactosylceramidase
GRN granulin
GSN gelsolin
HBB hemoglobin, beta
HBD hemoglobin, delta
HEY1 hes-related family bHLH transcription factor with YRPW motif 1
IGF1R insulin-like growth factor 1 receptor
IGF2BP2 insulin-like growth factor 2 mRNA binding protein 2
IL7R interleukin 7 receptor
INSR insulin receptor
JAG1 jagged 1
KRT18 keratin 18, type I
KRT19 keratin 19, type I
KRT8 keratin 8, type II
LDOC1 leucine zipper, down-regulated in cancer 1
LGALS3 lectin, galactoside-binding, soluble, 3
LHFP lipoma HMGIC fusion partner
LXN latexin
MAN1C1 mannosidase, alpha, class 1C, member 1
MAOB monoamine oxidase B
MBNL2 muscleblind-like splicing regulator 2
MED13L mediator complex subunit 13-like
MET MET proto-oncogene, receptor tyrosine kinase
MXRA7 matrix-remodelling associated 7
NEBL nebulette
NET1 neuroepithelial cell transforming 1
NR2F1 nuclear receptor subfamily 2, group F, member 1
NRP1 neuropilin 1
OLFM4 olfactomedin 4
PDGFC platelet derived growth factor C
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
PPAP2B phosphatidic acid phosphatase type 2B
PRSS23 protease, serine, 23
S100P S100 calcium binding protein P
SEMA3C sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C
SEPP1 selenoprotein P, plasma, 1
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
SMAD3 SMAD family member 3
SPARCL1 SPARC-like 1 (hevin)
SPOCK2 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2
TACSTD2 tumor-associated calcium signal transducer 2
TBX3 T-box 3
TFAP2A transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)
TIMP3 TIMP metallopeptidase inhibitor 3
TSPAN13 tetraspanin 13
TUBA1A tubulin, alpha 1a
TXNIP thioredoxin interacting protein
VNN1 vanin 1
VWF von Willebrand factor
XIST X inactive specific transcript (non-protein coding)
ZNF331 zinc finger protein 331

decreased expression

Symbol Name
BNIP3 BCL2/adenovirus E1B 19kDa interacting protein 3
CHRNA9 cholinergic receptor, nicotinic, alpha 9 (neuronal)
DMTF1 cyclin D binding myb-like transcription factor 1
FABP5 fatty acid binding protein 5 (psoriasis-associated)
FGL2 fibrinogen-like 2
FOLR1 folate receptor 1 (adult)
GAL galanin/GMAP prepropeptide
GPI glucose-6-phosphate isomerase
GUSBP3 glucuronidase, beta pseudogene 3
HP haptoglobin
KIF14 kinesin family member 14
MAPKAPK3 mitogen-activated protein kinase-activated protein kinase 3
ME2 malic enzyme 2, NAD(+)-dependent, mitochondrial
MT1M metallothionein 1M
POLE2 polymerase (DNA directed), epsilon 2, accessory subunit
RPS4Y1 ribosomal protein S4, Y-linked 1
S100A2 S100 calcium binding protein A2
SFN stratifin
SLC4A4 solute carrier family 4 (sodium bicarbonate cotransporter), member 4
TRAPPC3 trafficking protein particle complex 3