BRD-A25736793_everolimus_MCF7_24_h_3.33_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

89 genes differentially expressed following the BRD-A25736793_everolimus_MCF7_24_h_3.33_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
AGR2 anterior gradient 2
ASPN asporin
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group)
CD9 CD9 molecule
CDH1 cadherin 1, type 1, E-cadherin (epithelial)
CELF2 CUGBP, Elav-like family member 2
DDX3Y DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked
EFEMP1 EGF containing fibulin-like extracellular matrix protein 1
EFNA1 ephrin-A1
EIF1AY eukaryotic translation initiation factor 1A, Y-linked
GOLM1 golgi membrane protein 1
GREM1 gremlin 1, DAN family BMP antagonist
H2AFY H2A histone family, member Y
HIST1H4C histone cluster 1, H4c
HIST2H2BE histone cluster 2, H2be
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1
IFI16 interferon, gamma-inducible protein 16
KDM5D lysine (K)-specific demethylase 5D
KLF6 Kruppel-like factor 6
LDLR low density lipoprotein receptor
MAN2A1 mannosidase, alpha, class 2A, member 1
MTUS1 microtubule associated tumor suppressor 1
MYC v-myc avian myelocytomatosis viral oncogene homolog
NFIB nuclear factor I/B
NRIP1 nuclear receptor interacting protein 1
PHYH phytanoyl-CoA 2-hydroxylase
QKI QKI, KH domain containing, RNA binding
RPS4Y1 ribosomal protein S4, Y-linked 1
RRP12 ribosomal RNA processing 12 homolog (S. cerevisiae)
SC5D sterol-C5-desaturase
SRPX sushi-repeat containing protein, X-linked
ST3GAL5 ST3 beta-galactoside alpha-2,3-sialyltransferase 5
TFAP2B transcription factor AP-2 beta (activating enhancer binding protein 2 beta)
TRIM2 tripartite motif containing 2
TSC22D2 TSC22 domain family, member 2
TSPAN3 tetraspanin 3
TTC3 tetratricopeptide repeat domain 3
TUBB2A tubulin, beta 2A class IIa
TXNIP thioredoxin interacting protein
YBX3 Y box binding protein 3
YPEL5 yippee-like 5 (Drosophila)

decreased expression

Symbol Name
AGT angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
AKR1C3 aldo-keto reductase family 1, member C3
ATF5 activating transcription factor 5
C20ORF24 chromosome 20 open reading frame 24
C6ORF62 chromosome 6 open reading frame 62
CA12 carbonic anhydrase XII
CA2 carbonic anhydrase II
CCDC86 coiled-coil domain containing 86
CD24 CD24 molecule
CD58 CD58 molecule
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39)
CLEC5A C-type lectin domain family 5, member A
COTL1 coactosin-like F-actin binding protein 1
CREG1 cellular repressor of E1A-stimulated genes 1
CSTA cystatin A (stefin A)
CXCL3 chemokine (C-X-C motif) ligand 3
EIF1AX eukaryotic translation initiation factor 1A, X-linked
FADS2 fatty acid desaturase 2
FAM129A family with sequence similarity 129, member A
FAM46A family with sequence similarity 46, member A
FCER1A Fc fragment of IgE, high affinity I, receptor for; alpha polypeptide
G0S2 G0/G1 switch 2
GAL galanin/GMAP prepropeptide
GPI glucose-6-phosphate isomerase
GRWD1 glutamate-rich WD repeat containing 1
HK2 hexokinase 2
IER3 immediate early response 3
IFI30 interferon, gamma-inducible protein 30
KCNK3 potassium channel, two pore domain subfamily K, member 3
LOC100505650 uncharacterized LOC100505650
LPAR6 lysophosphatidic acid receptor 6
PGAM1 phosphoglycerate mutase 1 (brain)
POLR2I polymerase (RNA) II (DNA directed) polypeptide I, 14.5kDa
PRPF4 pre-mRNA processing factor 4
PSMD8 proteasome (prosome, macropain) 26S subunit, non-ATPase, 8
PTGDS prostaglandin D2 synthase 21kDa (brain)
PTGER4 prostaglandin E receptor 4 (subtype EP4)
S100A8 S100 calcium binding protein A8
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
SLC16A3 solute carrier family 16 (monocarboxylate transporter), member 3
SLC25A14 solute carrier family 25 (mitochondrial carrier, brain), member 14
SLPI secretory leukocyte peptidase inhibitor
TFRC transferrin receptor
TIMM17B translocase of inner mitochondrial membrane 17 homolog B (yeast)
TNFAIP6 tumor necrosis factor, alpha-induced protein 6
VEGFA vascular endothelial growth factor A
XIST X inactive specific transcript (non-protein coding)