BRD-A25736793_everolimus_MCF7_24_h_10_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
Similar Terms
Downloads & Tools

Genes

101 genes differentially expressed following the BRD-A25736793_everolimus_MCF7_24_h_10_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
AGR2 anterior gradient 2
ASAH1 N-acylsphingosine amidohydrolase (acid ceramidase) 1
BCAM basal cell adhesion molecule (Lutheran blood group)
CADM1 cell adhesion molecule 1
CCNA1 cyclin A1
CD9 CD9 molecule
CEP57 centrosomal protein 57kDa
CLU clusterin
CXCL12 chemokine (C-X-C motif) ligand 12
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1
DDB2 damage-specific DNA binding protein 2, 48kDa
DMTF1 cyclin D binding myb-like transcription factor 1
DSP desmoplakin
EGFR epidermal growth factor receptor
FST follistatin
GALNT7 polypeptide N-acetylgalactosaminyltransferase 7
GOLGA8A golgin A8 family, member A
GPNMB glycoprotein (transmembrane) nmb
GSN gelsolin
HIST2H2BE histone cluster 2, H2be
HIST3H2A histone cluster 3, H2a
HLA-DPA1 major histocompatibility complex, class II, DP alpha 1
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1
IGKC immunoglobulin kappa constant
IGL immunoglobulin lambda locus
ITGB5 integrin, beta 5
KRT19 keratin 19, type I
LPCAT1 lysophosphatidylcholine acyltransferase 1
LUM lumican
MAN2A1 mannosidase, alpha, class 2A, member 1
MLPH melanophilin
MYC v-myc avian myelocytomatosis viral oncogene homolog
NMU neuromedin U
PAN2 PAN2 poly(A) specific ribonuclease subunit
PAPD7 PAP associated domain containing 7
PAPSS2 3'-phosphoadenosine 5'-phosphosulfate synthase 2
PPL periplakin
RBM47 RNA binding motif protein 47
RELN reelin
RTN2 reticulon 2
SC5D sterol-C5-desaturase
SEPP1 selenoprotein P, plasma, 1
SH3YL1 SH3 and SYLF domain containing 1
SLC5A6 solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6
SORL1 sortilin-related receptor, L(DLR class) A repeats containing
SRD5A1 steroid-5-alpha-reductase, alpha polypeptide 1 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 1)
ST6GALNAC2 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
STOM stomatin
TACSTD2 tumor-associated calcium signal transducer 2
TFAP2B transcription factor AP-2 beta (activating enhancer binding protein 2 beta)
TP53 tumor protein p53
TRAPPC6A trafficking protein particle complex 6A
TSPAN13 tetraspanin 13
TTC3 tetratricopeptide repeat domain 3
TUSC3 tumor suppressor candidate 3
TXNIP thioredoxin interacting protein
UBE3B ubiquitin protein ligase E3B
YPEL5 yippee-like 5 (Drosophila)

decreased expression

Symbol Name
ADH5 alcohol dehydrogenase 5 (class III), chi polypeptide
BAG2 BCL2-associated athanogene 2
C6ORF62 chromosome 6 open reading frame 62
CALML4 calmodulin-like 4
CCDC86 coiled-coil domain containing 86
CCT2 chaperonin containing TCP1, subunit 2 (beta)
COL1A2 collagen, type I, alpha 2
COL2A1 collagen, type II, alpha 1
CREG1 cellular repressor of E1A-stimulated genes 1
CXCL14 chemokine (C-X-C motif) ligand 14
CYCS cytochrome c, somatic
EIF5 eukaryotic translation initiation factor 5
ENO1 enolase 1, (alpha)
FADS1 fatty acid desaturase 1
FADS2 fatty acid desaturase 2
GEM GTP binding protein overexpressed in skeletal muscle
GRWD1 glutamate-rich WD repeat containing 1
HOXC10 homeobox C10
ID3 inhibitor of DNA binding 3, dominant negative helix-loop-helix protein
ITGA6 integrin, alpha 6
ITM2A integral membrane protein 2A
LGALS1 lectin, galactoside-binding, soluble, 1
LMO4 LIM domain only 4
MLF1 myeloid leukemia factor 1
MUC4 mucin 4, cell surface associated
NTRK2 neurotrophic tyrosine kinase, receptor, type 2
PIGB phosphatidylinositol glycan anchor biosynthesis, class B
PLK1 polo-like kinase 1
POSTN periostin, osteoblast specific factor
PSMD13 proteasome (prosome, macropain) 26S subunit, non-ATPase, 13
PSPH phosphoserine phosphatase
RCAN2 regulator of calcineurin 2
SCRG1 stimulator of chondrogenesis 1
SDC2 syndecan 2
SLC25A14 solute carrier family 25 (mitochondrial carrier, brain), member 14
SLC33A1 solute carrier family 33 (acetyl-CoA transporter), member 1
SLC7A5 solute carrier family 7 (amino acid transporter light chain, L system), member 5
TCTN1 tectonic family member 1
TPD52 tumor protein D52
TRA2B transformer 2 beta homolog (Drosophila)
UBE2S ubiquitin-conjugating enzyme E2S
VPS28 vacuolar protein sorting 28 homolog (S. cerevisiae)