BRD-A25736793_everolimus_MCF7_24_h_0.12_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

67 genes differentially expressed following the BRD-A25736793_everolimus_MCF7_24_h_0.12_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
BTG2 BTG family, member 2
C10ORF10 chromosome 10 open reading frame 10
CCL4 chemokine (C-C motif) ligand 4
CCL5 chemokine (C-C motif) ligand 5
CCND2 cyclin D2
CD52 CD52 molecule
CEACAM5 carcinoembryonic antigen-related cell adhesion molecule 5
CEACAM6 carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen)
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1
CXCL13 chemokine (C-X-C motif) ligand 13
DKK3 dickkopf WNT signaling pathway inhibitor 3
EPB41L3 erythrocyte membrane protein band 4.1-like 3
FHOD3 formin homology 2 domain containing 3
FN1 fibronectin 1
GABRP gamma-aminobutyric acid (GABA) A receptor, pi
GSPT2 G1 to S phase transition 2
GSTM3 glutathione S-transferase mu 3 (brain)
HECA headcase homolog (Drosophila)
HNMT histamine N-methyltransferase
HOPX HOP homeobox
HTRA1 HtrA serine peptidase 1
IER5 immediate early response 5
LAMP3 lysosomal-associated membrane protein 3
LPAR2 lysophosphatidic acid receptor 2
MARCKSL1 MARCKS-like 1
NID1 nidogen 1
NOTCH2NL notch 2 N-terminal like
PDCD4 programmed cell death 4 (neoplastic transformation inhibitor)
PITPNC1 phosphatidylinositol transfer protein, cytoplasmic 1
POSTN periostin, osteoblast specific factor
RASGRP1 RAS guanyl releasing protein 1 (calcium and DAG-regulated)
SCUBE2 signal peptide, CUB domain, EGF-like 2
SEL1L3 sel-1 suppressor of lin-12-like 3 (C. elegans)
SERPINA3 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3
SPATA20 spermatogenesis associated 20
SPINK2 serine peptidase inhibitor, Kazal type 2 (acrosin-trypsin inhibitor)
TFPI2 tissue factor pathway inhibitor 2
TMEM158 transmembrane protein 158 (gene/pseudogene)
TRBC1 T cell receptor beta constant 1
XYLT1 xylosyltransferase I

decreased expression

Symbol Name
AKR1B10 aldo-keto reductase family 1, member B10 (aldose reductase)
AKR1C1 aldo-keto reductase family 1, member C1
AKR1C2 aldo-keto reductase family 1, member C2
AKR1C3 aldo-keto reductase family 1, member C3
AQP1 aquaporin 1 (Colton blood group)
EIF4G1 eukaryotic translation initiation factor 4 gamma, 1
EIF5A eukaryotic translation initiation factor 5A
EPHA3 EPH receptor A3
GABRE gamma-aminobutyric acid (GABA) A receptor, epsilon
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
HSPD1 heat shock 60kDa protein 1 (chaperonin)
IQGAP1 IQ motif containing GTPase activating protein 1
KRT7 keratin 7, type II
MAGEA12 melanoma antigen family A12
MAGEA3 melanoma antigen family A3
MAGEA6 melanoma antigen family A6
MAPKAPK3 mitogen-activated protein kinase-activated protein kinase 3
NR2F2 nuclear receptor subfamily 2, group F, member 2
ODC1 ornithine decarboxylase 1
RHOB ras homolog family member B
SHC1 SHC (Src homology 2 domain containing) transforming protein 1
TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)
TPPP3 tubulin polymerization-promoting protein family member 3
VAT1 vesicle amine transport 1
VCAM1 vascular cell adhesion molecule 1
YWHAE tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon