BRD-A25736793_everolimus_HT29_24_h_10_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

83 genes differentially expressed following the BRD-A25736793_everolimus_HT29_24_h_10_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ABCC3 ATP-binding cassette, sub-family C (CFTR/MRP), member 3
ACSM3 acyl-CoA synthetase medium-chain family member 3
ACTB actin, beta
ADCK3 aarF domain containing kinase 3
ANK3 ankyrin 3, node of Ranvier (ankyrin G)
C1ORF106 chromosome 1 open reading frame 106
C2CD5 C2 calcium-dependent domain containing 5
CAPG capping protein (actin filament), gelsolin-like
CCL21 chemokine (C-C motif) ligand 21
CD24 CD24 molecule
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group)
CDH1 cadherin 1, type 1, E-cadherin (epithelial)
CLIC4 chloride intracellular channel 4
COL1A1 collagen, type I, alpha 1
CTSA cathepsin A
CTSE cathepsin E
DDX3Y DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked
DEFB1 defensin, beta 1
DST dystonin
FCGBP Fc fragment of IgG binding protein
FOXO4 forkhead box O4
GAP43 growth associated protein 43
GATM glycine amidinotransferase (L-arginine:glycine amidinotransferase)
HLA-DMA major histocompatibility complex, class II, DM alpha
HSPA2 heat shock 70kDa protein 2
IFI27 interferon, alpha-inducible protein 27
IGFBP1 insulin-like growth factor binding protein 1
IGHD immunoglobulin heavy constant delta
IRF9 interferon regulatory factor 9
ITGB4 integrin, beta 4
KCNK1 potassium channel, two pore domain subfamily K, member 1
LAD1 ladinin 1
LGALS3 lectin, galactoside-binding, soluble, 3
LGALS3BP lectin, galactoside-binding, soluble, 3 binding protein
MAGED1 melanoma antigen family D1
MARCKS myristoylated alanine-rich protein kinase C substrate
MFSD10 major facilitator superfamily domain containing 10
NGFRAP1 nerve growth factor receptor (TNFRSF16) associated protein 1
PIGB phosphatidylinositol glycan anchor biosynthesis, class B
PLS3 plastin 3
PNMA2 paraneoplastic Ma antigen 2
PRKCA protein kinase C, alpha
PRUNE2 prune homolog 2 (Drosophila)
QSOX1 quiescin Q6 sulfhydryl oxidase 1
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B
SFRP4 secreted frizzled-related protein 4
SFTPA2 surfactant protein A2
SFTPB surfactant protein B
SOX11 SRY (sex determining region Y)-box 11
SPINK1 serine peptidase inhibitor, Kazal type 1
SPON2 spondin 2, extracellular matrix protein
SULT1C2 sulfotransferase family, cytosolic, 1C, member 2
TACSTD2 tumor-associated calcium signal transducer 2
TCFL5 transcription factor-like 5 (basic helix-loop-helix)
TMEM176B transmembrane protein 176B
TMEM255A transmembrane protein 255A
TMEM45A transmembrane protein 45A
TUBA1A tubulin, alpha 1a
VAT1 vesicle amine transport 1
WDTC1 WD and tetratricopeptide repeats 1
XK X-linked Kx blood group
ZMYND8 zinc finger, MYND-type containing 8

decreased expression

Symbol Name
ARHGDIA Rho GDP dissociation inhibitor (GDI) alpha
ATP8B1 ATPase, aminophospholipid transporter, class I, type 8B, member 1
C6ORF62 chromosome 6 open reading frame 62
CCND2 cyclin D2
CRIM1 cysteine rich transmembrane BMP regulator 1 (chordin-like)
DKK3 dickkopf WNT signaling pathway inhibitor 3
EPAS1 endothelial PAS domain protein 1
FASN fatty acid synthase
FKBP5 FK506 binding protein 5
IFRD2 interferon-related developmental regulator 2
MBOAT7 membrane bound O-acyltransferase domain containing 7
MMP3 matrix metallopeptidase 3
PRPF4 pre-mRNA processing factor 4
SLC1A1 solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1
SMC1A structural maintenance of chromosomes 1A
STOM stomatin
THBS1 thrombospondin 1
TSPAN13 tetraspanin 13
XIST X inactive specific transcript (non-protein coding)
YWHAE tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon