BRD-A25736793_everolimus_HT29_24_h_1.11_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

72 genes differentially expressed following the BRD-A25736793_everolimus_HT29_24_h_1.11_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ANK3 ankyrin 3, node of Ranvier (ankyrin G)
BDH2 3-hydroxybutyrate dehydrogenase, type 2
BIK BCL2-interacting killer (apoptosis-inducing)
BLNK B-cell linker
C14ORF132 chromosome 14 open reading frame 132
C2CD5 C2 calcium-dependent domain containing 5
C4BPA complement component 4 binding protein, alpha
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39)
CHL1 cell adhesion molecule L1-like
CP ceruloplasmin (ferroxidase)
CRISP3 cysteine-rich secretory protein 3
CYP4B1 cytochrome P450, family 4, subfamily B, polypeptide 1
DDX17 DEAD (Asp-Glu-Ala-Asp) box helicase 17
DUSP10 dual specificity phosphatase 10
DUSP6 dual specificity phosphatase 6
FOLR1 folate receptor 1 (adult)
FOXO4 forkhead box O4
GPNMB glycoprotein (transmembrane) nmb
GPR137B G protein-coupled receptor 137B
HNMT histamine N-methyltransferase
HOXA5 homeobox A5
HOXB2 homeobox B2
HOXC6 homeobox C6
IFI27 interferon, alpha-inducible protein 27
IFI44L interferon-induced protein 44-like
IFIT1 interferon-induced protein with tetratricopeptide repeats 1
IFITM1 interferon induced transmembrane protein 1
IGFBP2 insulin-like growth factor binding protein 2, 36kDa
ISG15 ISG15 ubiquitin-like modifier
LAT2 linker for activation of T cells family, member 2
LY96 lymphocyte antigen 96
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
MB myoglobin
MEIS1 Meis homeobox 1
MFAP5 microfibrillar associated protein 5
MKNK2 MAP kinase interacting serine/threonine kinase 2
NDUFB4 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 4, 15kDa
PLA2G16 phospholipase A2, group XVI
PRUNE2 prune homolog 2 (Drosophila)
RBP1 retinol binding protein 1, cellular
SCGB2A1 secretoglobin, family 2A, member 1
SOX11 SRY (sex determining region Y)-box 11
TBL1X transducin (beta)-like 1X-linked
TMSB15A thymosin beta 15a
TOX thymocyte selection-associated high mobility group box
TPD52L1 tumor protein D52-like 1
TSPAN6 tetraspanin 6
TST thiosulfate sulfurtransferase (rhodanese)
UGT2B15 UDP glucuronosyltransferase 2 family, polypeptide B15
WDTC1 WD and tetratricopeptide repeats 1
ZFPM2 zinc finger protein, FOG family member 2

decreased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
AKR1C1 aldo-keto reductase family 1, member C1
AKR1C2 aldo-keto reductase family 1, member C2
AKR1C3 aldo-keto reductase family 1, member C3
CFD complement factor D (adipsin)
COL15A1 collagen, type XV, alpha 1
CSGALNACT1 chondroitin sulfate N-acetylgalactosaminyltransferase 1
CYTL1 cytokine-like 1
FASN fatty acid synthase
GJA1 gap junction protein, alpha 1, 43kDa
HSPA4L heat shock 70kDa protein 4-like
IFRD1 interferon-related developmental regulator 1
IFRD2 interferon-related developmental regulator 2
KRT14 keratin 14, type I
KRT17 keratin 17, type I
PDXK pyridoxal (pyridoxine, vitamin B6) kinase
RNH1 ribonuclease/angiogenin inhibitor 1
SOX9 SRY (sex determining region Y)-box 9
SRGN serglycin
TM4SF1 transmembrane 4 L six family member 1
TRH thyrotropin-releasing hormone