BRD-A25736793_everolimus_HEPG2_24_h_10_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
Similar Terms
Downloads & Tools

Genes

61 genes differentially expressed following the BRD-A25736793_everolimus_HEPG2_24_h_10_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ABAT 4-aminobutyrate aminotransferase
ASPN asporin
C10ORF10 chromosome 10 open reading frame 10
CAMK2N1 calcium/calmodulin-dependent protein kinase II inhibitor 1
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39)
EGR3 early growth response 3
EMP1 epithelial membrane protein 1
ENO1 enolase 1, (alpha)
EPCAM epithelial cell adhesion molecule
FGFR1 fibroblast growth factor receptor 1
FHL1 four and a half LIM domains 1
FLI1 Fli-1 proto-oncogene, ETS transcription factor
GATA2 GATA binding protein 2
GC group-specific component (vitamin D binding protein)
HLA-DPA1 major histocompatibility complex, class II, DP alpha 1
HLA-DRA major histocompatibility complex, class II, DR alpha
HOOK2 hook microtubule-tethering protein 2
ID4 inhibitor of DNA binding 4, dominant negative helix-loop-helix protein
IFI16 interferon, gamma-inducible protein 16
IFITM1 interferon induced transmembrane protein 1
IGHM immunoglobulin heavy constant mu
IL7R interleukin 7 receptor
ISG15 ISG15 ubiquitin-like modifier
JCHAIN joining chain of multimeric IgA and IgM
LAMC1 laminin, gamma 1 (formerly LAMB2)
LBP lipopolysaccharide binding protein
LY96 lymphocyte antigen 96
MICAL2 microtubule associated monooxygenase, calponin and LIM domain containing 2
MSRA methionine sulfoxide reductase A
MX1 MX dynamin-like GTPase 1
PCK1 phosphoenolpyruvate carboxykinase 1 (soluble)
POSTN periostin, osteoblast specific factor
PTN pleiotrophin
RCAN1 regulator of calcineurin 1
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
SFRP4 secreted frizzled-related protein 4
SORBS1 sorbin and SH3 domain containing 1
SRSF6 serine/arginine-rich splicing factor 6
THBS1 thrombospondin 1
THBS2 thrombospondin 2
TNC tenascin C

decreased expression

Symbol Name
CEACAM5 carcinoembryonic antigen-related cell adhesion molecule 5
CEACAM6 carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen)
CSTA cystatin A (stefin A)
EFNA1 ephrin-A1
GATM glycine amidinotransferase (L-arginine:glycine amidinotransferase)
HMOX1 heme oxygenase 1
KLK11 kallikrein-related peptidase 11
MAL mal, T-cell differentiation protein
MB myoglobin
MSMB microseminoprotein, beta-
MSMO1 methylsterol monooxygenase 1
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
ODC1 ornithine decarboxylase 1
PLAGL1 pleiomorphic adenoma gene-like 1
POLR2I polymerase (RNA) II (DNA directed) polypeptide I, 14.5kDa
QPCT glutaminyl-peptide cyclotransferase
SHB Src homology 2 domain containing adaptor protein B
TFF3 trefoil factor 3 (intestinal)
TGFBI transforming growth factor, beta-induced, 68kDa