BRD-A25736793_everolimus_HCC515_24_h_3.33_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
Similar Terms
Downloads & Tools

Genes

103 genes differentially expressed following the BRD-A25736793_everolimus_HCC515_24_h_3.33_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ADIRF adipogenesis regulatory factor
AKR1C1 aldo-keto reductase family 1, member C1
AKR1C2 aldo-keto reductase family 1, member C2
AKR1C3 aldo-keto reductase family 1, member C3
AMOTL2 angiomotin like 2
ATHL1 ATH1, acid trehalase-like 1 (yeast)
BHLHE41 basic helix-loop-helix family, member e41
CAMLG calcium modulating ligand
CCDC92 coiled-coil domain containing 92
COL11A1 collagen, type XI, alpha 1
CPT1A carnitine palmitoyltransferase 1A (liver)
CRIP1 cysteine-rich protein 1 (intestinal)
CRISP3 cysteine-rich secretory protein 3
DAAM2 dishevelled associated activator of morphogenesis 2
DNAJC6 DnaJ (Hsp40) homolog, subfamily C, member 6
DUSP6 dual specificity phosphatase 6
DYNLT3 dynein, light chain, Tctex-type 3
ENPP2 ectonucleotide pyrophosphatase/phosphodiesterase 2
FAM171A1 family with sequence similarity 171, member A1
GAS6 growth arrest-specific 6
HMOX1 heme oxygenase 1
IDS iduronate 2-sulfatase
IRS1 insulin receptor substrate 1
LDOC1 leucine zipper, down-regulated in cancer 1
LEPROT leptin receptor overlapping transcript
LTBP2 latent transforming growth factor beta binding protein 2
MSLN mesothelin
MUC5B mucin 5B, oligomeric mucus/gel-forming
NGFRAP1 nerve growth factor receptor (TNFRSF16) associated protein 1
NPC2 Niemann-Pick disease, type C2
NQO1 NAD(P)H dehydrogenase, quinone 1
PBXIP1 pre-B-cell leukemia homeobox interacting protein 1
PDGFC platelet derived growth factor C
PNMA1 paraneoplastic Ma antigen 1
PRAF2 PRA1 domain family, member 2
PXDN peroxidasin
RBM3 RNA binding motif (RNP1, RRM) protein 3
SCG5 secretogranin V
SERPINI1 serpin peptidase inhibitor, clade I (neuroserpin), member 1
SHC1 SHC (Src homology 2 domain containing) transforming protein 1
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
SPINK1 serine peptidase inhibitor, Kazal type 1
SULT1C2 sulfotransferase family, cytosolic, 1C, member 2
TNS3 tensin 3
TPP1 tripeptidyl peptidase I
TSC22D3 TSC22 domain family, member 3
TSKU tsukushi, small leucine rich proteoglycan
UCHL1 ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)
VCAM1 vascular cell adhesion molecule 1
WDTC1 WD and tetratricopeptide repeats 1

decreased expression

Symbol Name
AGPAT5 1-acylglycerol-3-phosphate O-acyltransferase 5
ALOX15B arachidonate 15-lipoxygenase, type B
ATP1B1 ATPase, Na+/K+ transporting, beta 1 polypeptide
AZGP1 alpha-2-glycoprotein 1, zinc-binding
BDH1 3-hydroxybutyrate dehydrogenase, type 1
CCL2 chemokine (C-C motif) ligand 2
CEACAM1 carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein)
COTL1 coactosin-like F-actin binding protein 1
DBI diazepam binding inhibitor (GABA receptor modulator, acyl-CoA binding protein)
DDIT4 DNA-damage-inducible transcript 4
DNAH3 dynein, axonemal, heavy chain 3
EIF5A eukaryotic translation initiation factor 5A
ELOVL2 ELOVL fatty acid elongase 2
EPHA3 EPH receptor A3
FABP5 fatty acid binding protein 5 (psoriasis-associated)
FABP7 fatty acid binding protein 7, brain
FAM46A family with sequence similarity 46, member A
FKSG49 FKSG49
GPM6A glycoprotein M6A
GYPC glycophorin C (Gerbich blood group)
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1
IGFBP3 insulin-like growth factor binding protein 3
IL1RN interleukin 1 receptor antagonist
LRRN3 leucine rich repeat neuronal 3
MALL mal, T-cell differentiation protein-like
NES nestin
NFIB nuclear factor I/B
NR1H2 nuclear receptor subfamily 1, group H, member 2
OPHN1 oligophrenin 1
PDLIM1 PDZ and LIM domain 1
PELI1 pellino E3 ubiquitin protein ligase 1
PLAC8 placenta-specific 8
PLK1 polo-like kinase 1
PLTP phospholipid transfer protein
PNO1 partner of NOB1 homolog (S. cerevisiae)
PNP purine nucleoside phosphorylase
PROM1 prominin 1
PTPRZ1 protein tyrosine phosphatase, receptor-type, Z polypeptide 1
RFC2 replication factor C (activator 1) 2, 40kDa
RNASET2 ribonuclease T2
RPS11 ribosomal protein S11
RPS6KA1 ribosomal protein S6 kinase, 90kDa, polypeptide 1
S100A10 S100 calcium binding protein A10
S100A7 S100 calcium binding protein A7
SCD5 stearoyl-CoA desaturase 5
SERHL2 serine hydrolase-like 2
SERPINB2 serpin peptidase inhibitor, clade B (ovalbumin), member 2
SRPX sushi-repeat containing protein, X-linked
TCL1A T-cell leukemia/lymphoma 1A
TFRC transferrin receptor
TMEM123 transmembrane protein 123
UGT2B28 UDP glucuronosyltransferase 2 family, polypeptide B28