BRD-A25736793_everolimus_HCC515_24_h_0.37_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

94 genes differentially expressed following the BRD-A25736793_everolimus_HCC515_24_h_0.37_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ALDH6A1 aldehyde dehydrogenase 6 family, member A1
AMIGO2 adhesion molecule with Ig-like domain 2
C6ORF48 chromosome 6 open reading frame 48
CAMLG calcium modulating ligand
CD1E CD1e molecule
CHIC2 cysteine-rich hydrophobic domain 2
CNPY3 canopy FGF signaling regulator 3
CTSD cathepsin D
EID1 EP300 interacting inhibitor of differentiation 1
GPX3 glutathione peroxidase 3
HDAC6 histone deacetylase 6
HIST1H2AC histone cluster 1, H2ac
HMOX1 heme oxygenase 1
IQGAP1 IQ motif containing GTPase activating protein 1
KYNU kynureninase
LEPROT leptin receptor overlapping transcript
LZTFL1 leucine zipper transcription factor-like 1
MARCKS myristoylated alanine-rich protein kinase C substrate
NUPR1 nuclear protein, transcriptional regulator, 1
OXA1L oxidase (cytochrome c) assembly 1-like
PABPN1 poly(A) binding protein, nuclear 1
PAPSS2 3'-phosphoadenosine 5'-phosphosulfate synthase 2
PCBP2 poly(rC) binding protein 2
PDE2A phosphodiesterase 2A, cGMP-stimulated
PIK3IP1 phosphoinositide-3-kinase interacting protein 1
PNMA1 paraneoplastic Ma antigen 1
SCAND1 SCAN domain containing 1
SLC2A10 solute carrier family 2 (facilitated glucose transporter), member 10
SLC38A1 solute carrier family 38, member 1
SORBS3 sorbin and SH3 domain containing 3
TSC22D3 TSC22 domain family, member 3
UBE3B ubiquitin protein ligase E3B
WDR7 WD repeat domain 7
WDTC1 WD and tetratricopeptide repeats 1

decreased expression

Symbol Name
ACAT2 acetyl-CoA acetyltransferase 2
ACTN2 actinin, alpha 2
ADGRL2 adhesion G protein-coupled receptor L2
AKAP12 A kinase (PRKA) anchor protein 12
ALOX5 arachidonate 5-lipoxygenase
APOB apolipoprotein B
ATG3 autophagy related 3
CAV1 caveolin 1, caveolae protein, 22kDa
CEACAM1 carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein)
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39)
CKM creatine kinase, muscle
COL9A3 collagen, type IX, alpha 3
CXCL8 chemokine (C-X-C motif) ligand 8
DEFA5 defensin, alpha 5, Paneth cell-specific
DES desmin
ELOVL2 ELOVL fatty acid elongase 2
EZH2 enhancer of zeste 2 polycomb repressive complex 2 subunit
FABP5 fatty acid binding protein 5 (psoriasis-associated)
FABP7 fatty acid binding protein 7, brain
FAM69A family with sequence similarity 69, member A
FGFR2 fibroblast growth factor receptor 2
FOSL1 FOS-like antigen 1
HBEGF heparin-binding EGF-like growth factor
HILPDA hypoxia inducible lipid droplet-associated
IGF1 insulin-like growth factor 1 (somatomedin C)
IGFBP3 insulin-like growth factor binding protein 3
IGHM immunoglobulin heavy constant mu
IGL immunoglobulin lambda locus
ITGA4 integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor)
ITM2A integral membrane protein 2A
JCHAIN joining chain of multimeric IgA and IgM
KIAA0226L KIAA0226-like
KLK11 kallikrein-related peptidase 11
LGALS3 lectin, galactoside-binding, soluble, 3
LTF lactotransferrin
LUM lumican
LYZ lysozyme
MYBPC1 myosin binding protein C, slow type
NEB nebulin
NES nestin
NTS neurotensin
PCOLCE2 procollagen C-endopeptidase enhancer 2
PDE4B phosphodiesterase 4B, cAMP-specific
PDLIM1 PDZ and LIM domain 1
PLA2G2A phospholipase A2, group IIA (platelets, synovial fluid)
PTGS1 prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)
PTP4A3 protein tyrosine phosphatase type IVA, member 3
SERPINB2 serpin peptidase inhibitor, clade B (ovalbumin), member 2
SERPINE2 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2
SLC16A1 solute carrier family 16 (monocarboxylate transporter), member 1
SLN sarcolipin
SORBS1 sorbin and SH3 domain containing 1
SPARC secreted protein, acidic, cysteine-rich (osteonectin)
TFRC transferrin receptor
TMEM158 transmembrane protein 158 (gene/pseudogene)
TPM4 tropomyosin 4
TPSAB1 tryptase alpha/beta 1
TPSB2 tryptase beta 2 (gene/pseudogene)
TTN titin