BRD-A25736793_everolimus_HCC515_24_h_0.04_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

76 genes differentially expressed following the BRD-A25736793_everolimus_HCC515_24_h_0.04_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
AHNAK AHNAK nucleoprotein
ANXA6 annexin A6
ARMCX1 armadillo repeat containing, X-linked 1
BEX1 brain expressed, X-linked 1
C6ORF48 chromosome 6 open reading frame 48
CAPN1 calpain 1, (mu/I) large subunit
CCDC92 coiled-coil domain containing 92
CIRBP cold inducible RNA binding protein
CLDN10 claudin 10
CRIP1 cysteine-rich protein 1 (intestinal)
CRISP3 cysteine-rich secretory protein 3
EPHX1 epoxide hydrolase 1, microsomal (xenobiotic)
FIS1 fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae)
GPX3 glutathione peroxidase 3
HLA-DMA major histocompatibility complex, class II, DM alpha
HLA-DMB major histocompatibility complex, class II, DM beta
HMOX1 heme oxygenase 1
JUND jun D proto-oncogene
LCN2 lipocalin 2
LTBP3 latent transforming growth factor beta binding protein 3
MAGED1 melanoma antigen family D1
MAMLD1 mastermind-like domain containing 1
MDK midkine (neurite growth-promoting factor 2)
MGP matrix Gla protein
MTA1 metastasis associated 1
NID2 nidogen 2 (osteonidogen)
PAX8 paired box 8
PDZK1IP1 PDZK1 interacting protein 1
RGS10 regulator of G-protein signaling 10
RPS4Y1 ribosomal protein S4, Y-linked 1
SCNN1A sodium channel, non voltage gated 1 alpha subunit
SLPI secretory leukocyte peptidase inhibitor
SPINT1 serine peptidase inhibitor, Kunitz type 1
TSC22D3 TSC22 domain family, member 3
TXNIP thioredoxin interacting protein
WFDC2 WAP four-disulfide core domain 2
ZSCAN18 zinc finger and SCAN domain containing 18

decreased expression

Symbol Name
ACSL3 acyl-CoA synthetase long-chain family member 3
BCL2A1 BCL2-related protein A1
CEACAM1 carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein)
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39)
CKB creatine kinase, brain
CXCL14 chemokine (C-X-C motif) ligand 14
CXCL8 chemokine (C-X-C motif) ligand 8
CYP4B1 cytochrome P450, family 4, subfamily B, polypeptide 1
EDNRB endothelin receptor type B
EFEMP1 EGF containing fibulin-like extracellular matrix protein 1
EGLN3 egl-9 family hypoxia-inducible factor 3
FABP7 fatty acid binding protein 7, brain
FGFR2 fibroblast growth factor receptor 2
GEM GTP binding protein overexpressed in skeletal muscle
HBEGF heparin-binding EGF-like growth factor
HILPDA hypoxia inducible lipid droplet-associated
HPGD hydroxyprostaglandin dehydrogenase 15-(NAD)
HSPA4L heat shock 70kDa protein 4-like
IGFBP3 insulin-like growth factor binding protein 3
IL1RN interleukin 1 receptor antagonist
KDM3A lysine (K)-specific demethylase 3A
MMP12 matrix metallopeptidase 12
PNP purine nucleoside phosphorylase
PRPF4 pre-mRNA processing factor 4
PSPH phosphoserine phosphatase
PTGER4 prostaglandin E receptor 4 (subtype EP4)
PTPRZ1 protein tyrosine phosphatase, receptor-type, Z polypeptide 1
S100A9 S100 calcium binding protein A9
SLC16A1 solute carrier family 16 (monocarboxylate transporter), member 1
SLC2A5 solute carrier family 2 (facilitated glucose/fructose transporter), member 5
SLC5A6 solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6
SLCO4A1 solute carrier organic anion transporter family, member 4A1
TFAP2A transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)
TFRC transferrin receptor
TPD52 tumor protein D52
USP1 ubiquitin specific peptidase 1
VEGFA vascular endothelial growth factor A
XIST X inactive specific transcript (non-protein coding)