BRD-A25736793_everolimus_HA1E_24_h_3.33_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

103 genes differentially expressed following the BRD-A25736793_everolimus_HA1E_24_h_3.33_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
AKT3 v-akt murine thymoma viral oncogene homolog 3
ALCAM activated leukocyte cell adhesion molecule
AMIGO2 adhesion molecule with Ig-like domain 2
AMOTL2 angiomotin like 2
ANXA3 annexin A3
ATP9A ATPase, class II, type 9A
BEX1 brain expressed, X-linked 1
CBX7 chromobox homolog 7
CCNE2 cyclin E2
CDK5RAP3 CDK5 regulatory subunit associated protein 3
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CNN1 calponin 1, basic, smooth muscle
CX3CL1 chemokine (C-X3-C motif) ligand 1
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1
DACT1 dishevelled-binding antagonist of beta-catenin 1
EDN1 endothelin 1
EFEMP1 EGF containing fibulin-like extracellular matrix protein 1
FDFT1 farnesyl-diphosphate farnesyltransferase 1
GABRP gamma-aminobutyric acid (GABA) A receptor, pi
GADD45B growth arrest and DNA-damage-inducible, beta
GDF15 growth differentiation factor 15
GIMAP6 GTPase, IMAP family member 6
GOLGA8H golgin A8 family, member H
HIST1H4C histone cluster 1, H4c
HOOK2 hook microtubule-tethering protein 2
HOXA5 homeobox A5
ID4 inhibitor of DNA binding 4, dominant negative helix-loop-helix protein
IFT27 intraflagellar transport 27
INHBA inhibin, beta A
IQGAP1 IQ motif containing GTPase activating protein 1
KDELR3 KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 3
KRT17 keratin 17, type I
KRT18 keratin 18, type I
KRT19 keratin 19, type I
KRT7 keratin 7, type II
LXN latexin
MARCH6 membrane-associated ring finger (C3HC4) 6, E3 ubiquitin protein ligase
MDFIC MyoD family inhibitor domain containing
MTA1 metastasis associated 1
MYC v-myc avian myelocytomatosis viral oncogene homolog
OLFM4 olfactomedin 4
PAN2 PAN2 poly(A) specific ribonuclease subunit
PEG10 paternally expressed 10
PLK2 polo-like kinase 2
PROM1 prominin 1
RGS4 regulator of G-protein signaling 4
RPS6KA5 ribosomal protein S6 kinase, 90kDa, polypeptide 5
SERPINA3 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3
SFRP1 secreted frizzled-related protein 1
SLC5A6 solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6
SLC6A14 solute carrier family 6 (amino acid transporter), member 14
SNCA synuclein, alpha (non A4 component of amyloid precursor)
TARBP1 TAR (HIV-1) RNA binding protein 1
TPM2 tropomyosin 2 (beta)
TRD T cell receptor delta locus
TRDV3 T cell receptor delta variable 3
WDTC1 WD and tetratricopeptide repeats 1
ZBTB18 zinc finger and BTB domain containing 18
ZDHHC11 zinc finger, DHHC-type containing 11

decreased expression

Symbol Name
ABCC4 ATP-binding cassette, sub-family C (CFTR/MRP), member 4
ATF5 activating transcription factor 5
BNIP3 BCL2/adenovirus E1B 19kDa interacting protein 3
BPHL biphenyl hydrolase-like (serine hydrolase)
BZW2 basic leucine zipper and W2 domains 2
CA12 carbonic anhydrase XII
CADM1 cell adhesion molecule 1
CBR1 carbonyl reductase 1
DDIT4 DNA-damage-inducible transcript 4
DEGS1 delta(4)-desaturase, sphingolipid 1
DMTF1 cyclin D binding myb-like transcription factor 1
EIF5A eukaryotic translation initiation factor 5A
ENO1 enolase 1, (alpha)
ENPP1 ectonucleotide pyrophosphatase/phosphodiesterase 1
FADS2 fatty acid desaturase 2
FAH fumarylacetoacetate hydrolase (fumarylacetoacetase)
FAM162A family with sequence similarity 162, member A
GSTM3 glutathione S-transferase mu 3 (brain)
HILPDA hypoxia inducible lipid droplet-associated
HK1 hexokinase 1
HMOX1 heme oxygenase 1
HSPA8 heat shock 70kDa protein 8
IGFBP2 insulin-like growth factor binding protein 2, 36kDa
KRT1 keratin 1, type II
LOC100505650 uncharacterized LOC100505650
MAF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog
MT1M metallothionein 1M
NLRP2 NLR family, pyrin domain containing 2
NVL nuclear VCP-like
OXSR1 oxidative stress responsive 1
P4HA2 prolyl 4-hydroxylase, alpha polypeptide II
PAX8 paired box 8
PGK1 phosphoglycerate kinase 1
PGM1 phosphoglucomutase 1
PHGDH phosphoglycerate dehydrogenase
PRKCA protein kinase C, alpha
PSAT1 phosphoserine aminotransferase 1
RRP12 ribosomal RNA processing 12 homolog (S. cerevisiae)
SEMA3C sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C
SLC2A1 solute carrier family 2 (facilitated glucose transporter), member 1
SLC2A5 solute carrier family 2 (facilitated glucose/fructose transporter), member 5
SLC39A8 solute carrier family 39 (zinc transporter), member 8
ZMYM2 zinc finger, MYM-type 2