BRD-A25736793_everolimus_HA1E_24_h_1.11_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

96 genes differentially expressed following the BRD-A25736793_everolimus_HA1E_24_h_1.11_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
AKT3 v-akt murine thymoma viral oncogene homolog 3
ALDH1A3 aldehyde dehydrogenase 1 family, member A3
ALDOB aldolase B, fructose-bisphosphate
AZGP1 alpha-2-glycoprotein 1, zinc-binding
CCNG2 cyclin G2
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CPS1 carbamoyl-phosphate synthase 1, mitochondrial
CYTL1 cytokine-like 1
DKK1 dickkopf WNT signaling pathway inhibitor 1
DSP desmoplakin
EDN3 endothelin 3
EGR1 early growth response 1
FLRT2 fibronectin leucine rich transmembrane protein 2
FST follistatin
GAS1 growth arrest-specific 1
GNA11 guanine nucleotide binding protein (G protein), alpha 11 (Gq class)
ID3 inhibitor of DNA binding 3, dominant negative helix-loop-helix protein
ID4 inhibitor of DNA binding 4, dominant negative helix-loop-helix protein
INHBA inhibin, beta A
KCNN4 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 4
KRT6B keratin 6B, type II
KRT7 keratin 7, type II
MTA1 metastasis associated 1
MYC v-myc avian myelocytomatosis viral oncogene homolog
PAN2 PAN2 poly(A) specific ribonuclease subunit
PEG10 paternally expressed 10
RAB31 RAB31, member RAS oncogene family
RTN2 reticulon 2
SERPINA3 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3
SFRP1 secreted frizzled-related protein 1
SHC1 SHC (Src homology 2 domain containing) transforming protein 1
SLC27A2 solute carrier family 27 (fatty acid transporter), member 2
SLK STE20-like kinase
STOM stomatin
TM4SF1 transmembrane 4 L six family member 1
TPM2 tropomyosin 2 (beta)
TRD T cell receptor delta locus
TRDV3 T cell receptor delta variable 3
ZBTB18 zinc finger and BTB domain containing 18

decreased expression

Symbol Name
ADI1 acireductone dioxygenase 1
ALDOC aldolase C, fructose-bisphosphate
ASNS asparagine synthetase (glutamine-hydrolyzing)
BNIP3 BCL2/adenovirus E1B 19kDa interacting protein 3
CA9 carbonic anhydrase IX
CMAHP cytidine monophospho-N-acetylneuraminic acid hydroxylase, pseudogene
DDIT4 DNA-damage-inducible transcript 4
EGLN3 egl-9 family hypoxia-inducible factor 3
EIF5 eukaryotic translation initiation factor 5
ENO1 enolase 1, (alpha)
EPHA3 EPH receptor A3
ESR1 estrogen receptor 1
FAM162A family with sequence similarity 162, member A
FBP1 fructose-1,6-bisphosphatase 1
FGFR2 fibroblast growth factor receptor 2
FRZB frizzled-related protein
GARS glycyl-tRNA synthetase
GBP1 guanylate binding protein 1, interferon-inducible
GLDC glycine dehydrogenase (decarboxylating)
HILPDA hypoxia inducible lipid droplet-associated
HIST1H2BC histone cluster 1, H2bc
HK2 hexokinase 2
HMOX1 heme oxygenase 1
ITGAE integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide)
JCHAIN joining chain of multimeric IgA and IgM
JMJD6 jumonji domain containing 6
LEFTY1 left-right determination factor 1
LTA4H leukotriene A4 hydrolase
MFAP5 microfibrillar associated protein 5
MPZL2 myelin protein zero-like 2
NDUFA4L2 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 4-like 2
PAX8 paired box 8
PCOLCE2 procollagen C-endopeptidase enhancer 2
PGM1 phosphoglucomutase 1
PHGDH phosphoglycerate dehydrogenase
PLBD1 phospholipase B domain containing 1
PNP purine nucleoside phosphorylase
PRKCH protein kinase C, eta
PRPF4 pre-mRNA processing factor 4
PSAT1 phosphoserine aminotransferase 1
PTGDS prostaglandin D2 synthase 21kDa (brain)
RGCC regulator of cell cycle
RPL39L ribosomal protein L39-like
SEMA3C sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C
SLC25A46 solute carrier family 25, member 46
SLC2A1 solute carrier family 2 (facilitated glucose transporter), member 1
SLC39A8 solute carrier family 39 (zinc transporter), member 8
SLC7A5 solute carrier family 7 (amino acid transporter light chain, L system), member 5
SPAG4 sperm associated antigen 4
SPON2 spondin 2, extracellular matrix protein
STK17B serine/threonine kinase 17b
STS steroid sulfatase (microsomal), isozyme S
SUB1 SUB1 homolog (S. cerevisiae)
TFRC transferrin receptor
WFDC2 WAP four-disulfide core domain 2
ZW10 zw10 kinetochore protein