BRD-A25736793_everolimus_A549_24_h_0.12_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

48 genes differentially expressed following the BRD-A25736793_everolimus_A549_24_h_0.12_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ACTA2 actin, alpha 2, smooth muscle, aorta
AGR2 anterior gradient 2
ALCAM activated leukocyte cell adhesion molecule
ALDH1A3 aldehyde dehydrogenase 1 family, member A3
C3ORF14 chromosome 3 open reading frame 14
CCDC92 coiled-coil domain containing 92
CD99 CD99 molecule
CST1 cystatin SN
CTGF connective tissue growth factor
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1
DCN decorin
DSP desmoplakin
DUSP1 dual specificity phosphatase 1
EPCAM epithelial cell adhesion molecule
ERBB2 erb-b2 receptor tyrosine kinase 2
FN1 fibronectin 1
GALC galactosylceramidase
GNAS GNAS complex locus
GSTZ1 glutathione S-transferase zeta 1
IFITM1 interferon induced transmembrane protein 1
KLF6 Kruppel-like factor 6
LAMB1 laminin, beta 1
MDFIC MyoD family inhibitor domain containing
MDK midkine (neurite growth-promoting factor 2)
PBXIP1 pre-B-cell leukemia homeobox interacting protein 1
PDGFD platelet derived growth factor D
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
TCEA2 transcription elongation factor A (SII), 2
TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)
TRAPPC6A trafficking protein particle complex 6A
YPEL5 yippee-like 5 (Drosophila)

decreased expression

Symbol Name
ACAT2 acetyl-CoA acetyltransferase 2
ASNS asparagine synthetase (glutamine-hydrolyzing)
BCL2A1 BCL2-related protein A1
CALML4 calmodulin-like 4
CCNB2 cyclin B2
GUCY1A3 guanylate cyclase 1, soluble, alpha 3
IGKC immunoglobulin kappa constant
IGL immunoglobulin lambda locus
JCHAIN joining chain of multimeric IgA and IgM
NTRK2 neurotrophic tyrosine kinase, receptor, type 2
PHGDH phosphoglycerate dehydrogenase
PPAT phosphoribosyl pyrophosphate amidotransferase
PPP1R3C protein phosphatase 1, regulatory subunit 3C
PSAT1 phosphoserine aminotransferase 1
PYCR1 pyrroline-5-carboxylate reductase 1
TMEM45A transmembrane protein 45A