BRD-A25569250_S1315_ASC_24.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

63 genes differentially expressed following the BRD-A25569250_S1315_ASC_24.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
CA2 carbonic anhydrase II
CAMK2N1 calcium/calmodulin-dependent protein kinase II inhibitor 1
CELF2 CUGBP, Elav-like family member 2
CPE carboxypeptidase E
CRABP2 cellular retinoic acid binding protein 2
EMC2 ER membrane protein complex subunit 2
GATA6 GATA binding protein 6
GLUL glutamate-ammonia ligase
GULP1 GULP, engulfment adaptor PTB domain containing 1
JAG1 jagged 1
KCTD12 potassium channel tetramerization domain containing 12
PDGFD platelet derived growth factor D
PEG3 paternally expressed 3
SCD stearoyl-CoA desaturase (delta-9-desaturase)
TRD T cell receptor delta locus
TRDV3 T cell receptor delta variable 3

decreased expression

Symbol Name
ANXA3 annexin A3
ANXA6 annexin A6
AXL AXL receptor tyrosine kinase
BIRC5 baculoviral IAP repeat containing 5
CCNA2 cyclin A2
CD59 CD59 molecule, complement regulatory protein
CDC20 cell division cycle 20
CDH2 cadherin 2, type 1, N-cadherin (neuronal)
CDK1 cyclin-dependent kinase 1
CEACAM1 carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein)
COTL1 coactosin-like F-actin binding protein 1
CSRP1 cysteine and glycine-rich protein 1
CXCL8 chemokine (C-X-C motif) ligand 8
DKK1 dickkopf WNT signaling pathway inhibitor 1
FOLR1 folate receptor 1 (adult)
FOSL1 FOS-like antigen 1
IFI6 interferon, alpha-inducible protein 6
IGF2BP3 insulin-like growth factor 2 mRNA binding protein 3
ITGA6 integrin, alpha 6
ITGB5 integrin, beta 5
KIF20A kinesin family member 20A
KRT7 keratin 7, type II
MAP7 microtubule-associated protein 7
NME4 NME/NM23 nucleoside diphosphate kinase 4
NNMT nicotinamide N-methyltransferase
NQO1 NAD(P)H dehydrogenase, quinone 1
PFKP phosphofructokinase, platelet
PODXL podocalyxin-like
PTTG1 pituitary tumor-transforming 1
PTX3 pentraxin 3, long
PVALB parvalbumin
RCAN1 regulator of calcineurin 1
RPS11 ribosomal protein S11
S100A6 S100 calcium binding protein A6
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
SLC15A2 solute carrier family 15 (oligopeptide transporter), member 2
SLC7A1 solute carrier family 7 (cationic amino acid transporter, y+ system), member 1
SYNM synemin, intermediate filament protein
TJP2 tight junction protein 2
TM4SF1 transmembrane 4 L six family member 1
TPM1 tropomyosin 1 (alpha)
TPX2 TPX2, microtubule-associated
TYMS thymidylate synthetase
UBE2C ubiquitin-conjugating enzyme E2C
UBE2S ubiquitin-conjugating enzyme E2S
UBE3C ubiquitin protein ligase E3C