BRD-A25337146_-666_SKB_24.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

47 genes differentially expressed following the BRD-A25337146_-666_SKB_24.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ARFIP2 ADP-ribosylation factor interacting protein 2
CD163 CD163 molecule
CLIC4 chloride intracellular channel 4
CTSL cathepsin L
EPHA3 EPH receptor A3
FKBP10 FK506 binding protein 10, 65 kDa
HMGA2 high mobility group AT-hook 2
HMOX1 heme oxygenase 1
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1
HSPA1A heat shock 70kDa protein 1A
LAPTM5 lysosomal protein transmembrane 5
MAP7 microtubule-associated protein 7
MECOM MDS1 and EVI1 complex locus
MT1M metallothionein 1M
NNMT nicotinamide N-methyltransferase
NRIP1 nuclear receptor interacting protein 1
PCOLCE procollagen C-endopeptidase enhancer
PLA2G2A phospholipase A2, group IIA (platelets, synovial fluid)
PLOD2 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2
RPS4Y1 ribosomal protein S4, Y-linked 1
S100A2 S100 calcium binding protein A2
SH3TC1 SH3 domain and tetratricopeptide repeats 1
SPTLC2 serine palmitoyltransferase, long chain base subunit 2
SRGN serglycin
TM4SF1 transmembrane 4 L six family member 1

decreased expression

Symbol Name
ADH1B alcohol dehydrogenase 1B (class I), beta polypeptide
AREG amphiregulin
CAV1 caveolin 1, caveolae protein, 22kDa
CAV2 caveolin 2
CDC25B cell division cycle 25B
CEACAM6 carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen)
CITED2 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2
CLU clusterin
FGF13 fibroblast growth factor 13
IGFBP5 insulin-like growth factor binding protein 5
NPY1R neuropeptide Y receptor Y1
PDZD8 PDZ domain containing 8
RAB11FIP2 RAB11 family interacting protein 2 (class I)
RAB31 RAB31, member RAS oncogene family
RRM2 ribonucleotide reductase M2
S100P S100 calcium binding protein P
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
SSR4 signal sequence receptor, delta
TCF7L2 transcription factor 7-like 2 (T-cell specific, HMG-box)
TMSB15A thymosin beta 15a
ZNF185 zinc finger protein 185 (LIM domain)