BRD-A25337146_-666_MCF7_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
Similar Terms
Downloads & Tools

Genes

117 genes differentially expressed following the BRD-A25337146_-666_MCF7_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ABCB6 ATP-binding cassette, sub-family B (MDR/TAP), member 6 (Langereis blood group)
ABHD4 abhydrolase domain containing 4
ADM adrenomedullin
AKR1C1 aldo-keto reductase family 1, member C1
AKR1C2 aldo-keto reductase family 1, member C2
AREG amphiregulin
ASNS asparagine synthetase (glutamine-hydrolyzing)
ATF3 activating transcription factor 3
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group)
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1
CXCL8 chemokine (C-X-C motif) ligand 8
DDIT3 DNA-damage-inducible transcript 3
DNAJB1 DnaJ (Hsp40) homolog, subfamily B, member 1
EGLN3 egl-9 family hypoxia-inducible factor 3
FOSL1 FOS-like antigen 1
FTH1 ferritin, heavy polypeptide 1
GCLM glutamate-cysteine ligase, modifier subunit
GPX2 glutathione peroxidase 2
HCAR3 hydroxycarboxylic acid receptor 3
HMOX1 heme oxygenase 1
HSPA1A heat shock 70kDa protein 1A
HSPA6 heat shock 70kDa protein 6 (HSP70B')
HSPH1 heat shock 105kDa/110kDa protein 1
HTATIP2 HIV-1 Tat interactive protein 2, 30kDa
IFRD1 interferon-related developmental regulator 1
KLF4 Kruppel-like factor 4 (gut)
KLF6 Kruppel-like factor 6
MMP3 matrix metallopeptidase 3
NFIL3 nuclear factor, interleukin 3 regulated
PHLDA1 pleckstrin homology-like domain, family A, member 1
PKP1 plakophilin 1
PLAUR plasminogen activator, urokinase receptor
PLIN2 perilipin 2
PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1
PPP1R15A protein phosphatase 1, regulatory subunit 15A
SERPINH1 serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1)
SLC1A4 solute carrier family 1 (glutamate/neutral amino acid transporter), member 4
SLC3A2 solute carrier family 3 (amino acid transporter heavy chain), member 2
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
SLC7A7 solute carrier family 7 (amino acid transporter light chain, y+L system), member 7
SPRR3 small proline-rich protein 3
TBC1D31 TBC1 domain family, member 31
TGFBI transforming growth factor, beta-induced, 68kDa
TNFRSF12A tumor necrosis factor receptor superfamily, member 12A
TRIB1 tribbles pseudokinase 1
TRIB3 tribbles pseudokinase 3
TUBB2A tubulin, beta 2A class IIa
TXNRD1 thioredoxin reductase 1
WARS tryptophanyl-tRNA synthetase
WNT5A wingless-type MMTV integration site family, member 5A
ZFP36 ZFP36 ring finger protein

decreased expression

Symbol Name
ABCD3 ATP-binding cassette, sub-family D (ALD), member 3
ACTG2 actin, gamma 2, smooth muscle, enteric
ADAMDEC1 ADAM-like, decysin 1
AEBP1 AE binding protein 1
ARHGAP29 Rho GTPase activating protein 29
ARHGEF3 Rho guanine nucleotide exchange factor (GEF) 3
BASP1 brain abundant, membrane attached signal protein 1
C3 complement component 3
C7 complement component 7
CCL19 chemokine (C-C motif) ligand 19
CNN1 calponin 1, basic, smooth muscle
COL4A5 collagen, type IV, alpha 5
CP ceruloplasmin (ferroxidase)
DCN decorin
DPT dermatopontin
DPYD dihydropyrimidine dehydrogenase
DPYSL3 dihydropyrimidinase-like 3
ESR1 estrogen receptor 1
FHL1 four and a half LIM domains 1
FLRT2 fibronectin leucine rich transmembrane protein 2
GBAS glioblastoma amplified sequence
GBP1 guanylate binding protein 1, interferon-inducible
GPD1L glycerol-3-phosphate dehydrogenase 1-like
GPRC5B G protein-coupled receptor, class C, group 5, member B
IFITM3 interferon induced transmembrane protein 3
IL33 interleukin 33
ITPR1 inositol 1,4,5-trisphosphate receptor, type 1
KCTD12 potassium channel tetramerization domain containing 12
LGALS1 lectin, galactoside-binding, soluble, 1
LGALS3BP lectin, galactoside-binding, soluble, 3 binding protein
LTBP1 latent transforming growth factor beta binding protein 1
LXN latexin
MARCKSL1 MARCKS-like 1
MEIS1 Meis homeobox 1
MEIS2 Meis homeobox 2
MFAP5 microfibrillar associated protein 5
MGP matrix Gla protein
MYH11 myosin, heavy chain 11, smooth muscle
NAV2 neuron navigator 2
NFIB nuclear factor I/B
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
NR2F1 nuclear receptor subfamily 2, group F, member 1
OGN osteoglycin
PCP4 Purkinje cell protein 4
PTGIS prostaglandin I2 (prostacyclin) synthase
RARRES1 retinoic acid receptor responder (tazarotene induced) 1
RARRES2 retinoic acid receptor responder (tazarotene induced) 2
RFX5 regulatory factor X, 5 (influences HLA class II expression)
SCNN1A sodium channel, non voltage gated 1 alpha subunit
SERPINA5 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5
SFRP1 secreted frizzled-related protein 1
SFRP4 secreted frizzled-related protein 4
SLC15A2 solute carrier family 15 (oligopeptide transporter), member 2
SLC29A1 solute carrier family 29 (equilibrative nucleoside transporter), member 1
SLPI secretory leukocyte peptidase inhibitor
SORL1 sortilin-related receptor, L(DLR class) A repeats containing
STK26 serine/threonine protein kinase 26
TACSTD2 tumor-associated calcium signal transducer 2
TCFL5 transcription factor-like 5 (basic helix-loop-helix)
TGFBR2 transforming growth factor, beta receptor II (70/80kDa)
TM4SF1 transmembrane 4 L six family member 1
VNN1 vanin 1
WFDC2 WAP four-disulfide core domain 2
XBP1 X-box binding protein 1