Dataset | LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules |
Category | transcriptomics |
Type | small molecule perturbation |
Description | small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map) |
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100 genes differentially expressed following the BRD-A25337146_-666_HT29_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
Symbol | Name |
---|---|
1060P11.3 | killer cell immunoglobulin-like receptor, three domains, pseudogene |
ADM | adrenomedullin |
AKR1B10 | aldo-keto reductase family 1, member B10 (aldose reductase) |
AKR1C1 | aldo-keto reductase family 1, member C1 |
AKR1C2 | aldo-keto reductase family 1, member C2 |
BAG3 | BCL2-associated athanogene 3 |
BPHL | biphenyl hydrolase-like (serine hydrolase) |
CBR3 | carbonyl reductase 3 |
CDKN1A | cyclin-dependent kinase inhibitor 1A (p21, Cip1) |
CEBPA | CCAAT/enhancer binding protein (C/EBP), alpha |
CHI3L1 | chitinase 3-like 1 (cartilage glycoprotein-39) |
CP | ceruloplasmin (ferroxidase) |
CTSL | cathepsin L |
CXCL8 | chemokine (C-X-C motif) ligand 8 |
DDIT4 | DNA-damage-inducible transcript 4 |
DNAJB1 | DnaJ (Hsp40) homolog, subfamily B, member 1 |
ENPP1 | ectonucleotide pyrophosphatase/phosphodiesterase 1 |
FOSL1 | FOS-like antigen 1 |
GCLC | glutamate-cysteine ligase, catalytic subunit |
GCLM | glutamate-cysteine ligase, modifier subunit |
HMOX1 | heme oxygenase 1 |
HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 |
HSPA1A | heat shock 70kDa protein 1A |
HSPA6 | heat shock 70kDa protein 6 (HSP70B') |
HSPA8 | heat shock 70kDa protein 8 |
HSPH1 | heat shock 105kDa/110kDa protein 1 |
IER5 | immediate early response 5 |
IGFBP2 | insulin-like growth factor binding protein 2, 36kDa |
IL6R | interleukin 6 receptor |
JMJD6 | jumonji domain containing 6 |
JUN | jun proto-oncogene |
LAPTM4B | lysosomal protein transmembrane 4 beta |
LST1 | leukocyte specific transcript 1 |
ME1 | malic enzyme 1, NADP(+)-dependent, cytosolic |
MT1F | metallothionein 1F |
MT1X | metallothionein 1X |
MYC | v-myc avian myelocytomatosis viral oncogene homolog |
NQO1 | NAD(P)H dehydrogenase, quinone 1 |
PRNP | prion protein |
PTX3 | pentraxin 3, long |
SERPINH1 | serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1) |
SFN | stratifin |
SH3TC1 | SH3 domain and tetratricopeptide repeats 1 |
SLC30A1 | solute carrier family 30 (zinc transporter), member 1 |
SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 |
SQSTM1 | sequestosome 1 |
TRIM16 | tripartite motif containing 16 |
TXN | thioredoxin |
TXNRD1 | thioredoxin reductase 1 |
UGDH | UDP-glucose 6-dehydrogenase |
UPP1 | uridine phosphorylase 1 |
VEGFA | vascular endothelial growth factor A |
Symbol | Name |
---|---|
ADAMTS1 | ADAM metallopeptidase with thrombospondin type 1 motif, 1 |
ADD3 | adducin 3 (gamma) |
ADH1B | alcohol dehydrogenase 1B (class I), beta polypeptide |
ANOS1 | anosmin 1 |
ARL6IP5 | ADP-ribosylation factor-like 6 interacting protein 5 |
ASCL1 | achaete-scute family bHLH transcription factor 1 |
B3GNT1 | |
BEX1 | brain expressed, X-linked 1 |
CHN2 | chimerin 2 |
CHRDL1 | chordin-like 1 |
DDB2 | damage-specific DNA binding protein 2, 48kDa |
DEPTOR | DEP domain containing MTOR-interacting protein |
ERBB2 | erb-b2 receptor tyrosine kinase 2 |
FAM13A | family with sequence similarity 13, member A |
FHL1 | four and a half LIM domains 1 |
HEY1 | hes-related family bHLH transcription factor with YRPW motif 1 |
HPGD | hydroxyprostaglandin dehydrogenase 15-(NAD) |
KRT7 | keratin 7, type II |
LAMB1 | laminin, beta 1 |
LMO3 | LIM domain only 3 (rhombotin-like 2) |
MARCKS | myristoylated alanine-rich protein kinase C substrate |
MET | MET proto-oncogene, receptor tyrosine kinase |
METTL7A | methyltransferase like 7A |
NDN | necdin, melanoma antigen (MAGE) family member |
NFIB | nuclear factor I/B |
NR2F1 | nuclear receptor subfamily 2, group F, member 1 |
NREP | neuronal regeneration related protein |
NRIP1 | nuclear receptor interacting protein 1 |
NUAK1 | NUAK family, SNF1-like kinase, 1 |
PDE1A | phosphodiesterase 1A, calmodulin-dependent |
PPARG | peroxisome proliferator-activated receptor gamma |
PTGER4 | prostaglandin E receptor 4 (subtype EP4) |
PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) |
PURA | purine-rich element binding protein A |
QPCT | glutaminyl-peptide cyclotransferase |
REG1A | regenerating islet-derived 1 alpha |
REG3A | regenerating islet-derived 3 alpha |
RGS13 | regulator of G-protein signaling 13 |
RGS2 | regulator of G-protein signaling 2 |
SALL2 | spalt-like transcription factor 2 |
SORL1 | sortilin-related receptor, L(DLR class) A repeats containing |
SOX4 | SRY (sex determining region Y)-box 4 |
SWAP70 | SWAP switching B-cell complex 70kDa subunit |
TCF4 | transcription factor 4 |
TFF1 | trefoil factor 1 |
TNIK | TRAF2 and NCK interacting kinase |
TSPAN13 | tetraspanin 13 |
VCAN | versican |