BRD-A25170757_1-(4,5-bis(benzyloxy)-2-fluorophenyl)-2-(methylamino)ethanol KLK-33_VCAP_24.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

40 genes differentially expressed following the BRD-A25170757_1-(4,5-bis(benzyloxy)-2-fluorophenyl)-2-(methylamino)ethanol KLK-33_VCAP_24.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ASPN asporin
BPIFA1 BPI fold containing family A, member 1
C3ORF14 chromosome 3 open reading frame 14
CEACAM6 carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen)
EBP emopamil binding protein (sterol isomerase)
ELOVL6 ELOVL fatty acid elongase 6
FDFT1 farnesyl-diphosphate farnesyltransferase 1
GADD45B growth arrest and DNA-damage-inducible, beta
INSIG1 insulin induced gene 1
LDLR low density lipoprotein receptor
MAPKAPK5 mitogen-activated protein kinase-activated protein kinase 5
MXI1 MAX interactor 1, dimerization protein
PFN2 profilin 2
RAP1GAP RAP1 GTPase activating protein
RAP2A RAP2A, member of RAS oncogene family
THBS2 thrombospondin 2

decreased expression

Symbol Name
ALOX5AP arachidonate 5-lipoxygenase-activating protein
ASRGL1 asparaginase like 1
C1QA complement component 1, q subcomponent, A chain
C1S complement component 1, s subcomponent
CA2 carbonic anhydrase II
CD69 CD69 molecule
CDK1 cyclin-dependent kinase 1
CLU clusterin
CXCL13 chemokine (C-X-C motif) ligand 13
FABP5 fatty acid binding protein 5 (psoriasis-associated)
G0S2 G0/G1 switch 2
ITGA6 integrin, alpha 6
LITAF lipopolysaccharide-induced TNF factor
LYZ lysozyme
MAP7 microtubule-associated protein 7
MEOX2 mesenchyme homeobox 2
PLK2 polo-like kinase 2
PTGDS prostaglandin D2 synthase 21kDa (brain)
RGS13 regulator of G-protein signaling 13
SPARCL1 SPARC-like 1 (hevin)
TMEM176B transmembrane protein 176B
TSPAN4 tetraspanin 4
TYMS thymidylate synthetase