BRD-A25143711_HYDROCORTISONE VALERATE_HA1E_24.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

83 genes differentially expressed following the BRD-A25143711_HYDROCORTISONE VALERATE_HA1E_24.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ADGRF5 adhesion G protein-coupled receptor F5
AHNAK2 AHNAK nucleoprotein 2
AKAP1 A kinase (PRKA) anchor protein 1
ALDH2 aldehyde dehydrogenase 2 family (mitochondrial)
C3 complement component 3
CEBPD CCAAT/enhancer binding protein (C/EBP), delta
CHST15 carbohydrate (N-acetylgalactosamine 4-sulfate 6-O) sulfotransferase 15
CHST2 carbohydrate (N-acetylglucosamine-6-O) sulfotransferase 2
CLDN18 claudin 18
CLDN5 claudin 5
CPE carboxypeptidase E
CPM carboxypeptidase M
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1
DCN decorin
DDIT4 DNA-damage-inducible transcript 4
DDX3Y DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked
DMBT1 deleted in malignant brain tumors 1
EFEMP1 EGF containing fibulin-like extracellular matrix protein 1
EPAS1 endothelial PAS domain protein 1
FAIM Fas apoptotic inhibitory molecule
FGG fibrinogen gamma chain
FKBP5 FK506 binding protein 5
HERC5 HECT and RLD domain containing E3 ubiquitin protein ligase 5
HSD17B11 hydroxysteroid (17-beta) dehydrogenase 11
IFNGR1 interferon gamma receptor 1
KLF4 Kruppel-like factor 4 (gut)
LAMP3 lysosomal-associated membrane protein 3
LPL lipoprotein lipase
MAGEA3 melanoma antigen family A3
MBNL1 muscleblind-like splicing regulator 1
MSLN mesothelin
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
NNMT nicotinamide N-methyltransferase
P3H2 prolyl 3-hydroxylase 2
PFN2 profilin 2
PLBD1 phospholipase B domain containing 1
PNMA2 paraneoplastic Ma antigen 2
PRR15L proline rich 15-like
RPS4Y1 ribosomal protein S4, Y-linked 1
SCGB1D2 secretoglobin, family 1D, member 2
SCNN1A sodium channel, non voltage gated 1 alpha subunit
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
SFTPB surfactant protein B
SFTPC surfactant protein C
SGCE sarcoglycan, epsilon
SLPI secretory leukocyte peptidase inhibitor
TSC22D3 TSC22 domain family, member 3
TXNIP thioredoxin interacting protein
VCAN versican

decreased expression

Symbol Name
ADGRG1 adhesion G protein-coupled receptor G1
AGTR1 angiotensin II receptor, type 1
ALDH1A3 aldehyde dehydrogenase 1 family, member A3
APOD apolipoprotein D
BAALC brain and acute leukemia, cytoplasmic
CD24 CD24 molecule
COL11A1 collagen, type XI, alpha 1
EHF ets homologous factor
EPHA3 EPH receptor A3
HES1 hes family bHLH transcription factor 1
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1
IER3 immediate early response 3
IGFBP3 insulin-like growth factor binding protein 3
IL13RA2 interleukin 13 receptor, alpha 2
JCHAIN joining chain of multimeric IgA and IgM
MAP7 microtubule-associated protein 7
MARCKSL1 MARCKS-like 1
MMP12 matrix metallopeptidase 12
NR0B1 nuclear receptor subfamily 0, group B, member 1
RAD23B RAD23 homolog B (S. cerevisiae)
RTN3 reticulon 3
SERPINB3 serpin peptidase inhibitor, clade B (ovalbumin), member 3
SERPINB4 serpin peptidase inhibitor, clade B (ovalbumin), member 4
SPINK2 serine peptidase inhibitor, Kazal type 2 (acrosin-trypsin inhibitor)
ST3GAL5 ST3 beta-galactoside alpha-2,3-sialyltransferase 5
TCF4 transcription factor 4
TNC tenascin C
TPM4 tropomyosin 4
TSPAN13 tetraspanin 13
TUBB6 tubulin, beta 6 class V
UBE2J1 ubiquitin-conjugating enzyme E2, J1
WLS wntless Wnt ligand secretion mediator