BRD-A25143711_-666_A549_24.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
Similar Terms
Downloads & Tools

Genes

126 genes differentially expressed following the BRD-A25143711_-666_A549_24.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ABAT 4-aminobutyrate aminotransferase
ACSL1 acyl-CoA synthetase long-chain family member 1
ADIRF adipogenesis regulatory factor
AOX1 aldehyde oxidase 1
AREG amphiregulin
ASS1 argininosuccinate synthase 1
BBX bobby sox homolog (Drosophila)
CD14 CD14 molecule
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CFD complement factor D (adipsin)
CPM carboxypeptidase M
CRIP1 cysteine-rich protein 1 (intestinal)
CRYAB crystallin, alpha B
DDIT4 DNA-damage-inducible transcript 4
DDX17 DEAD (Asp-Glu-Ala-Asp) box helicase 17
DUSP1 dual specificity phosphatase 1
F13A1 coagulation factor XIII, A1 polypeptide
FCGBP Fc fragment of IgG binding protein
FKBP5 FK506 binding protein 5
FOLR1 folate receptor 1 (adult)
FOXO3 forkhead box O3
GLRX glutaredoxin (thioltransferase)
GPM6B glycoprotein M6B
HBB hemoglobin, beta
IFI27 interferon, alpha-inducible protein 27
KLF6 Kruppel-like factor 6
KLF9 Kruppel-like factor 9
LAMB1 laminin, beta 1
MCL1 myeloid cell leukemia 1
MFAP5 microfibrillar associated protein 5
MT1F metallothionein 1F
MT1M metallothionein 1M
MT1X metallothionein 1X
NCOA4 nuclear receptor coactivator 4
NEFM neurofilament, medium polypeptide
NELL2 NEL-like 2 (chicken)
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
NOL3 nucleolar protein 3 (apoptosis repressor with CARD domain)
NPY1R neuropeptide Y receptor Y1
ORAI3 ORAI calcium release-activated calcium modulator 3
P2RY14 purinergic receptor P2Y, G-protein coupled, 14
PDCD4 programmed cell death 4 (neoplastic transformation inhibitor)
PDLIM1 PDZ and LIM domain 1
PDZK1 PDZ domain containing 1
PER1 period circadian clock 1
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
PLA2G16 phospholipase A2, group XVI
PLOD2 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2
PRKCD protein kinase C, delta
PTCH1 patched 1
RASSF4 Ras association (RalGDS/AF-6) domain family member 4
RGS1 regulator of G-protein signaling 1
RGS2 regulator of G-protein signaling 2
RGS5 regulator of G-protein signaling 5
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
SGCB sarcoglycan, beta (43kDa dystrophin-associated glycoprotein)
SIDT2 SID1 transmembrane family, member 2
SLC26A2 solute carrier family 26 (anion exchanger), member 2
SLC31A2 solute carrier family 31 (copper transporter), member 2
SLPI secretory leukocyte peptidase inhibitor
STMN2 stathmin 2
SYBU syntabulin (syntaxin-interacting)
TSC22D3 TSC22 domain family, member 3
TSKU tsukushi, small leucine rich proteoglycan
TXNIP thioredoxin interacting protein
UCHL1 ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)
VCAN versican
VNN1 vanin 1
VSIG4 V-set and immunoglobulin domain containing 4
WIPI1 WD repeat domain, phosphoinositide interacting 1
ZBTB16 zinc finger and BTB domain containing 16
ZFP36 ZFP36 ring finger protein

decreased expression

Symbol Name
APP amyloid beta (A4) precursor protein
AURKA aurora kinase A
CCL2 chemokine (C-C motif) ligand 2
CDC25A cell division cycle 25A
CDC25B cell division cycle 25B
CDC6 cell division cycle 6
CEMIP cell migration inducing protein, hyaluronan binding
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1
CIT citron rho-interacting serine/threonine kinase
CSRP2 cysteine and glycine-rich protein 2
CTSZ cathepsin Z
DLK1 delta-like 1 homolog (Drosophila)
EZH2 enhancer of zeste 2 polycomb repressive complex 2 subunit
FABP5 fatty acid binding protein 5 (psoriasis-associated)
FAM129A family with sequence similarity 129, member A
FAM57A family with sequence similarity 57, member A
FOSL1 FOS-like antigen 1
FST follistatin
FSTL1 follistatin-like 1
GALNT6 polypeptide N-acetylgalactosaminyltransferase 6
GDF15 growth differentiation factor 15
HMG20B high mobility group 20B
ID4 inhibitor of DNA binding 4, dominant negative helix-loop-helix protein
IER3 immediate early response 3
IGFBP3 insulin-like growth factor binding protein 3
IGHM immunoglobulin heavy constant mu
IGLV3-19 immunoglobulin lambda variable 3-19
KIF18B kinesin family member 18B
KIF20A kinesin family member 20A
LAMP3 lysosomal-associated membrane protein 3
LIG1 ligase I, DNA, ATP-dependent
LYPD1 LY6/PLAUR domain containing 1
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
MMP10 matrix metallopeptidase 10
PLK1 polo-like kinase 1
POLE2 polymerase (DNA directed), epsilon 2, accessory subunit
PSPH phosphoserine phosphatase
RAP1GAP RAP1 GTPase activating protein
RFC2 replication factor C (activator 1) 2, 40kDa
S100A7 S100 calcium binding protein A7
SCD stearoyl-CoA desaturase (delta-9-desaturase)
SERPINE2 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
SOX9 SRY (sex determining region Y)-box 9
SPAG5 sperm associated antigen 5
SPRY2 sprouty homolog 2 (Drosophila)
TFF3 trefoil factor 3 (intestinal)
TMEM158 transmembrane protein 158 (gene/pseudogene)
TNFRSF11B tumor necrosis factor receptor superfamily, member 11b
TOP2A topoisomerase (DNA) II alpha 170kDa
TPSAB1 tryptase alpha/beta 1
TPSB2 tryptase beta 2 (gene/pseudogene)
WNT5A wingless-type MMTV integration site family, member 5A