BRD-A25088322_-666_VCAP_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

33 genes differentially expressed following the BRD-A25088322_-666_VCAP_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ANPEP alanyl (membrane) aminopeptidase
CPD carboxypeptidase D
DNAJB1 DnaJ (Hsp40) homolog, subfamily B, member 1
FGB fibrinogen beta chain
HMOX1 heme oxygenase 1
HSPA1A heat shock 70kDa protein 1A
HSPA6 heat shock 70kDa protein 6 (HSP70B')
HTATIP2 HIV-1 Tat interactive protein 2, 30kDa
IRX5 iroquois homeobox 5
LAPTM4B lysosomal protein transmembrane 4 beta
LGALS3 lectin, galactoside-binding, soluble, 3
MYO1B myosin IB
NAMPT nicotinamide phosphoribosyltransferase
NGRN neugrin, neurite outgrowth associated
NRIP1 nuclear receptor interacting protein 1
PDGFC platelet derived growth factor C
PLEKHB1 pleckstrin homology domain containing, family B (evectins) member 1
SERPINH1 serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1)
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
SOX4 SRY (sex determining region Y)-box 4
TIMP3 TIMP metallopeptidase inhibitor 3
TXNRD1 thioredoxin reductase 1

decreased expression

Symbol Name
C7 complement component 7
EIF5A eukaryotic translation initiation factor 5A
FILIP1L filamin A interacting protein 1-like
HDAC9 histone deacetylase 9
MYH11 myosin, heavy chain 11, smooth muscle
PTGDS prostaglandin D2 synthase 21kDa (brain)
RGS5 regulator of G-protein signaling 5
TCF4 transcription factor 4
TLR4 toll-like receptor 4
VIM vimentin