BRD-A25088322_-666_MCF7_24.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

88 genes differentially expressed following the BRD-A25088322_-666_MCF7_24.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ABCB6 ATP-binding cassette, sub-family B (MDR/TAP), member 6 (Langereis blood group)
ABCC3 ATP-binding cassette, sub-family C (CFTR/MRP), member 3
ABHD4 abhydrolase domain containing 4
AKR1B10 aldo-keto reductase family 1, member B10 (aldose reductase)
AKR1C1 aldo-keto reductase family 1, member C1
AKR1C2 aldo-keto reductase family 1, member C2
ASS1 argininosuccinate synthase 1
CD44 CD44 molecule (Indian blood group)
CES1 carboxylesterase 1
CFD complement factor D (adipsin)
COCH cochlin
CXCL8 chemokine (C-X-C motif) ligand 8
DKK1 dickkopf WNT signaling pathway inhibitor 1
DUSP4 dual specificity phosphatase 4
DUSP5 dual specificity phosphatase 5
ERBB2 erb-b2 receptor tyrosine kinase 2
FGF13 fibroblast growth factor 13
FLNA filamin A, alpha
G6PD glucose-6-phosphate dehydrogenase
GABRE gamma-aminobutyric acid (GABA) A receptor, epsilon
GADD45A growth arrest and DNA-damage-inducible, alpha
GCLM glutamate-cysteine ligase, modifier subunit
HMOX1 heme oxygenase 1
HTATIP2 HIV-1 Tat interactive protein 2, 30kDa
IL7R interleukin 7 receptor
KRT7 keratin 7, type II
LYPD3 LY6/PLAUR domain containing 3
ME1 malic enzyme 1, NADP(+)-dependent, cytosolic
MXRA7 matrix-remodelling associated 7
NEBL nebulette
NQO1 NAD(P)H dehydrogenase, quinone 1
PHLDA2 pleckstrin homology-like domain, family A, member 2
PIR pirin (iron-binding nuclear protein)
RAP1GAP RAP1 GTPase activating protein
RND3 Rho family GTPase 3
S100P S100 calcium binding protein P
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
SMAD3 SMAD family member 3
TALDO1 transaldolase 1
TGM2 transglutaminase 2
TIMP1 TIMP metallopeptidase inhibitor 1
TRIM16 tripartite motif containing 16
TRIM29 tripartite motif containing 29
TSKU tsukushi, small leucine rich proteoglycan
TXNRD1 thioredoxin reductase 1
UBR4 ubiquitin protein ligase E3 component n-recognin 4

decreased expression

Symbol Name
ADD3 adducin 3 (gamma)
ADH5 alcohol dehydrogenase 5 (class III), chi polypeptide
ARMT1 acidic residue methyltransferase 1
CALD1 caldesmon 1
CDK1 cyclin-dependent kinase 1
CEP55 centrosomal protein 55kDa
CILP cartilage intermediate layer protein, nucleotide pyrophosphohydrolase
COL1A2 collagen, type I, alpha 2
COL3A1 collagen, type III, alpha 1
CXCL12 chemokine (C-X-C motif) ligand 12
ESR1 estrogen receptor 1
EVL Enah/Vasp-like
GADD45B growth arrest and DNA-damage-inducible, beta
GREB1 growth regulation by estrogen in breast cancer 1
GSTM3 glutathione S-transferase mu 3 (brain)
HADH hydroxyacyl-CoA dehydrogenase
HIST1H4C histone cluster 1, H4c
HLF hepatic leukemia factor
HOXC6 homeobox C6
IFITM2 interferon induced transmembrane protein 2
IFITM3 interferon induced transmembrane protein 3
ISOC1 isochorismatase domain containing 1
KIF20A kinesin family member 20A
LRIG1 leucine-rich repeats and immunoglobulin-like domains 1
MUC1 mucin 1, cell surface associated
NAT1 N-acetyltransferase 1 (arylamine N-acetyltransferase)
NBPF10 neuroblastoma breakpoint family, member 10
NREP neuronal regeneration related protein
PAN2 PAN2 poly(A) specific ribonuclease subunit
PDGFRL platelet-derived growth factor receptor-like
PLEKHJ1 pleckstrin homology domain containing, family J member 1
RAD51C RAD51 paralog C
RBM3 RNA binding motif (RNP1, RRM) protein 3
RMND1 required for meiotic nuclear division 1 homolog (S. cerevisiae)
SEPP1 selenoprotein P, plasma, 1
SFRP4 secreted frizzled-related protein 4
STMN1 stathmin 1
TMEM14A transmembrane protein 14A
TOP2A topoisomerase (DNA) II alpha 170kDa
VTCN1 V-set domain containing T cell activation inhibitor 1
WFDC2 WAP four-disulfide core domain 2