BRD-A25088322_-666_HT29_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

54 genes differentially expressed following the BRD-A25088322_-666_HT29_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ADM adrenomedullin
AKR1C1 aldo-keto reductase family 1, member C1
AKR1C2 aldo-keto reductase family 1, member C2
AKR1C3 aldo-keto reductase family 1, member C3
ALDH3A1 aldehyde dehydrogenase 3 family, member A1
AQP1 aquaporin 1 (Colton blood group)
ATF3 activating transcription factor 3
BAG3 BCL2-associated athanogene 3
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CEBPA CCAAT/enhancer binding protein (C/EBP), alpha
CFD complement factor D (adipsin)
DNAJB1 DnaJ (Hsp40) homolog, subfamily B, member 1
DUSP5 dual specificity phosphatase 5
EPHX1 epoxide hydrolase 1, microsomal (xenobiotic)
FOSL1 FOS-like antigen 1
GCLM glutamate-cysteine ligase, modifier subunit
HMGA1 high mobility group AT-hook 1
HMOX1 heme oxygenase 1
HPCAL1 hippocalcin-like 1
HSPA1A heat shock 70kDa protein 1A
HSPA6 heat shock 70kDa protein 6 (HSP70B')
HSPH1 heat shock 105kDa/110kDa protein 1
IER5 immediate early response 5
IFI27 interferon, alpha-inducible protein 27
IL6R interleukin 6 receptor
ME1 malic enzyme 1, NADP(+)-dependent, cytosolic
PCOLCE2 procollagen C-endopeptidase enhancer 2
S100A8 S100 calcium binding protein A8
S100P S100 calcium binding protein P
SLC30A1 solute carrier family 30 (zinc transporter), member 1
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
TSPAN7 tetraspanin 7
TXNRD1 thioredoxin reductase 1
UGDH UDP-glucose 6-dehydrogenase
YTHDF1 YTH N(6)-methyladenosine RNA binding protein 1

decreased expression

Symbol Name
ADGRL2 adhesion G protein-coupled receptor L2
ALCAM activated leukocyte cell adhesion molecule
BASP1 brain abundant, membrane attached signal protein 1
CSRP1 cysteine and glycine-rich protein 1
GATA2 GATA binding protein 2
HOXA5 homeobox A5
IFITM2 interferon induced transmembrane protein 2
KRT23 keratin 23, type I
LGALS3BP lectin, galactoside-binding, soluble, 3 binding protein
MARCKS myristoylated alanine-rich protein kinase C substrate
NRIP1 nuclear receptor interacting protein 1
RGS13 regulator of G-protein signaling 13
RGS2 regulator of G-protein signaling 2
RGS5 regulator of G-protein signaling 5
SOX4 SRY (sex determining region Y)-box 4
TNS3 tensin 3
TOP2A topoisomerase (DNA) II alpha 170kDa
XIST X inactive specific transcript (non-protein coding)