BRD-A25088322_-666_A375_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
Similar Terms
Downloads & Tools

Genes

105 genes differentially expressed following the BRD-A25088322_-666_A375_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ACKR3 atypical chemokine receptor 3
AKAP13 A kinase (PRKA) anchor protein 13
AKR1C1 aldo-keto reductase family 1, member C1
ATF3 activating transcription factor 3
ATF4 activating transcription factor 4
CADM1 cell adhesion molecule 1
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group)
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CEBPB CCAAT/enhancer binding protein (C/EBP), beta
CHIC2 cysteine-rich hydrophobic domain 2
CLDN10 claudin 10
COL1A1 collagen, type I, alpha 1
DDIT4 DNA-damage-inducible transcript 4
DLK1 delta-like 1 homolog (Drosophila)
DMBT1 deleted in malignant brain tumors 1
DNAJB2 DnaJ (Hsp40) homolog, subfamily B, member 2
DOK5 docking protein 5
DSG3 desmoglein 3
DUSP5 dual specificity phosphatase 5
EMP1 epithelial membrane protein 1
FAS Fas cell surface death receptor
FHL2 four and a half LIM domains 2
FOLR1 folate receptor 1 (adult)
FOSL2 FOS-like antigen 2
GAB2 GRB2-associated binding protein 2
GADD45A growth arrest and DNA-damage-inducible, alpha
GADD45B growth arrest and DNA-damage-inducible, beta
GLS glutaminase
GPX7 glutathione peroxidase 7
GSTA1 glutathione S-transferase alpha 1
GULP1 GULP, engulfment adaptor PTB domain containing 1
HMOX1 heme oxygenase 1
HSPA1A heat shock 70kDa protein 1A
HSPA6 heat shock 70kDa protein 6 (HSP70B')
JUN jun proto-oncogene
KLF2 Kruppel-like factor 2
KLF4 Kruppel-like factor 4 (gut)
KLF6 Kruppel-like factor 6
KRT14 keratin 14, type I
KRT5 keratin 5, type II
MEG3 maternally expressed 3 (non-protein coding)
MFAP5 microfibrillar associated protein 5
MMP1 matrix metallopeptidase 1
MUC5B mucin 5B, oligomeric mucus/gel-forming
MYC v-myc avian myelocytomatosis viral oncogene homolog
NFIL3 nuclear factor, interleukin 3 regulated
NR4A1 nuclear receptor subfamily 4, group A, member 1
ODC1 ornithine decarboxylase 1
PAPSS2 3'-phosphoadenosine 5'-phosphosulfate synthase 2
PDGFA platelet-derived growth factor alpha polypeptide
PENK proenkephalin
PPAP2B phosphatidic acid phosphatase type 2B
PPP1R15A protein phosphatase 1, regulatory subunit 15A
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B
RNMT RNA (guanine-7-) methyltransferase
SERTAD2 SERTA domain containing 2
SFN stratifin
SLC26A2 solute carrier family 26 (anion exchanger), member 2
SLC2A3 solute carrier family 2 (facilitated glucose transporter), member 3
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
SLC7A7 solute carrier family 7 (amino acid transporter light chain, y+L system), member 7
SPP1 secreted phosphoprotein 1
STC2 stanniocalcin 2
TXNRD1 thioredoxin reductase 1
XBP1 X-box binding protein 1
ZFP36 ZFP36 ring finger protein
ZFP36L2 ZFP36 ring finger protein-like 2
ZNF423 zinc finger protein 423

decreased expression

Symbol Name
A2M alpha-2-macroglobulin
ALDH1A3 aldehyde dehydrogenase 1 family, member A3
ALOX5 arachidonate 5-lipoxygenase
APMAP adipocyte plasma membrane associated protein
ARHGDIB Rho GDP dissociation inhibitor (GDI) beta
AURKA aurora kinase A
BASP1 brain abundant, membrane attached signal protein 1
BMI1 BMI1 proto-oncogene, polycomb ring finger
CCNA2 cyclin A2
CCNB1 cyclin B1
CCND1 cyclin D1
CCNE2 cyclin E2
CCNF cyclin F
CDC20 cell division cycle 20
CST7 cystatin F (leukocystatin)
CXCL13 chemokine (C-X-C motif) ligand 13
CXCL9 chemokine (C-X-C motif) ligand 9
ERBB3 erb-b2 receptor tyrosine kinase 3
IER3 immediate early response 3
IFITM3 interferon induced transmembrane protein 3
KIF20A kinesin family member 20A
KIF2C kinesin family member 2C
KPNA2 karyopherin alpha 2 (RAG cohort 1, importin alpha 1)
LGALS3BP lectin, galactoside-binding, soluble, 3 binding protein
NMU neuromedin U
PEG10 paternally expressed 10
PLK1 polo-like kinase 1
PLN phospholamban
POLR2L polymerase (RNA) II (DNA directed) polypeptide L, 7.6kDa
PTTG1 pituitary tumor-transforming 1
RARRES1 retinoic acid receptor responder (tazarotene induced) 1
RARRES3 retinoic acid receptor responder (tazarotene induced) 3
RRM2 ribonucleotide reductase M2
TIPARP TCDD-inducible poly(ADP-ribose) polymerase
TMEM2 transmembrane protein 2
TOP2A topoisomerase (DNA) II alpha 170kDa