BRD-A25067867_cogentin_HT29_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

51 genes differentially expressed following the BRD-A25067867_cogentin_HT29_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ALB albumin
C10ORF10 chromosome 10 open reading frame 10
CAV1 caveolin 1, caveolae protein, 22kDa
CD74 CD74 molecule, major histocompatibility complex, class II invariant chain
COLEC12 collectin sub-family member 12
CXCL10 chemokine (C-X-C motif) ligand 10
CXCL9 chemokine (C-X-C motif) ligand 9
FHOD3 formin homology 2 domain containing 3
FN1 fibronectin 1
GAGE3 G antigen 3
GATA3 GATA binding protein 3
GBP1 guanylate binding protein 1, interferon-inducible
GJA1 gap junction protein, alpha 1, 43kDa
GPER1 G protein-coupled estrogen receptor 1
IFI16 interferon, gamma-inducible protein 16
ITGA5 integrin, alpha 5 (fibronectin receptor, alpha polypeptide)
LDOC1 leucine zipper, down-regulated in cancer 1
MAGEA12 melanoma antigen family A12
MAGEA3 melanoma antigen family A3
MAGEA6 melanoma antigen family A6
MAN2A1 mannosidase, alpha, class 2A, member 1
MEF2C myocyte enhancer factor 2C
NDUFA4L2 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 4-like 2
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
STC1 stanniocalcin 1
TPM4 tropomyosin 4
UBE3B ubiquitin protein ligase E3B
XIST X inactive specific transcript (non-protein coding)

decreased expression

Symbol Name
ACOT9 acyl-CoA thioesterase 9
ALDH1A3 aldehyde dehydrogenase 1 family, member A3
ANXA3 annexin A3
AREG amphiregulin
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1)
CXCL1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)
CXCL8 chemokine (C-X-C motif) ligand 8
DKK1 dickkopf WNT signaling pathway inhibitor 1
EREG epiregulin
KDELR2 KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 2
KLF4 Kruppel-like factor 4 (gut)
MARCKS myristoylated alanine-rich protein kinase C substrate
NFIB nuclear factor I/B
PCDH9 protocadherin 9
PEBP1 phosphatidylethanolamine binding protein 1
PPIF peptidylprolyl isomerase F
RB1 retinoblastoma 1
RGS2 regulator of G-protein signaling 2
S100A7 S100 calcium binding protein A7
SLPI secretory leukocyte peptidase inhibitor
TESC tescalcin
TNPO1 transportin 1