BRD-A25004090_erastin_MCF7_24.0_h_4.8_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

23 genes differentially expressed following the BRD-A25004090_erastin_MCF7_24.0_h_4.8_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AARS alanyl-tRNA synthetase
ASNS asparagine synthetase (glutamine-hydrolyzing)
BCAM basal cell adhesion molecule (Lutheran blood group)
CREB3L2 cAMP responsive element binding protein 3-like 2
DDIT4 DNA-damage-inducible transcript 4
EIF4EBP1 eukaryotic translation initiation factor 4E binding protein 1
EPRS glutamyl-prolyl-tRNA synthetase
HMOX1 heme oxygenase 1
PAGE4 P antigen family, member 4 (prostate associated)
PCK2 phosphoenolpyruvate carboxykinase 2 (mitochondrial)
PDZK1IP1 PDZK1 interacting protein 1
PHGDH phosphoglycerate dehydrogenase
SHMT2 serine hydroxymethyltransferase 2 (mitochondrial)
TSC22D3 TSC22 domain family, member 3
VEGFA vascular endothelial growth factor A

decreased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
CA12 carbonic anhydrase XII
CELF2 CUGBP, Elav-like family member 2
HDHD1 haloacid dehalogenase-like hydrolase domain containing 1
ITGAE integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide)
MAPK6 mitogen-activated protein kinase 6
TFRC transferrin receptor
ZIC1 Zic family member 1