BRD-A25004090_erastin_HT29_24.0_h_4.8_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

63 genes differentially expressed following the BRD-A25004090_erastin_HT29_24.0_h_4.8_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ADAM28 ADAM metallopeptidase domain 28
ADM adrenomedullin
ALDH5A1 aldehyde dehydrogenase 5 family, member A1
ASNS asparagine synthetase (glutamine-hydrolyzing)
ASS1 argininosuccinate synthase 1
ATF4 activating transcription factor 4
C6ORF62 chromosome 6 open reading frame 62
CA2 carbonic anhydrase II
CBS cystathionine-beta-synthase
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1
CLIC4 chloride intracellular channel 4
CPE carboxypeptidase E
CXCL10 chemokine (C-X-C motif) ligand 10
DCN decorin
DDIT3 DNA-damage-inducible transcript 3
DDIT4 DNA-damage-inducible transcript 4
EIF4EBP1 eukaryotic translation initiation factor 4E binding protein 1
ETS2 v-ets avian erythroblastosis virus E26 oncogene homolog 2
FRZB frizzled-related protein
GARS glycyl-tRNA synthetase
GDF15 growth differentiation factor 15
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
HMOX1 heme oxygenase 1
HOXB2 homeobox B2
IFI27 interferon, alpha-inducible protein 27
IGKV4-1 immunoglobulin kappa variable 4-1
LOC100505650 uncharacterized LOC100505650
MARS methionyl-tRNA synthetase
MT1F metallothionein 1F
NPTX2 neuronal pentraxin II
NTRK2 neurotrophic tyrosine kinase, receptor, type 2
NUPR1 nuclear protein, transcriptional regulator, 1
PCK2 phosphoenolpyruvate carboxykinase 2 (mitochondrial)
PCSK1 proprotein convertase subtilisin/kexin type 1
PHGDH phosphoglycerate dehydrogenase
PSAT1 phosphoserine aminotransferase 1
RAB21 RAB21, member RAS oncogene family
RGCC regulator of cell cycle
RGS4 regulator of G-protein signaling 4
SCG5 secretogranin V
SHMT2 serine hydroxymethyltransferase 2 (mitochondrial)
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
SST somatostatin
TGFBI transforming growth factor, beta-induced, 68kDa
THY1 Thy-1 cell surface antigen
TMEM176B transmembrane protein 176B
TRIB3 tribbles pseudokinase 3
WARS tryptophanyl-tRNA synthetase
XPOT exportin, tRNA

decreased expression

Symbol Name
ACSL1 acyl-CoA synthetase long-chain family member 1
FHL1 four and a half LIM domains 1
FUCA1 fucosidase, alpha-L- 1, tissue
GOLGA8A golgin A8 family, member A
KIF1B kinesin family member 1B
LTF lactotransferrin
MYLK myosin light chain kinase
NFIB nuclear factor I/B
PDLIM5 PDZ and LIM domain 5
S100A10 S100 calcium binding protein A10
S100A11 S100 calcium binding protein A11
TGFBR2 transforming growth factor, beta receptor II (70/80kDa)
TM4SF1 transmembrane 4 L six family member 1