BRD-A25004090_erastin_HCC515_24.0_h_4.8_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

33 genes differentially expressed following the BRD-A25004090_erastin_HCC515_24.0_h_4.8_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
AARS alanyl-tRNA synthetase
ASNS asparagine synthetase (glutamine-hydrolyzing)
CTGF connective tissue growth factor
CTH cystathionine gamma-lyase
CXCL12 chemokine (C-X-C motif) ligand 12
EIF4EBP1 eukaryotic translation initiation factor 4E binding protein 1
ENPP1 ectonucleotide pyrophosphatase/phosphodiesterase 1
FCN1 ficolin (collagen/fibrinogen domain containing) 1
FGF13 fibroblast growth factor 13
GRB10 growth factor receptor-bound protein 10
HMOX1 heme oxygenase 1
IGKV4-1 immunoglobulin kappa variable 4-1
LTF lactotransferrin
PCK2 phosphoenolpyruvate carboxykinase 2 (mitochondrial)
PHGDH phosphoglycerate dehydrogenase
PSAT1 phosphoserine aminotransferase 1
PTPRO protein tyrosine phosphatase, receptor type, O
PYCR1 pyrroline-5-carboxylate reductase 1
SCGB2A2 secretoglobin, family 2A, member 2
SHMT2 serine hydroxymethyltransferase 2 (mitochondrial)
SLC1A4 solute carrier family 1 (glutamate/neutral amino acid transporter), member 4
TSC22D3 TSC22 domain family, member 3

decreased expression

Symbol Name
AMIGO2 adhesion molecule with Ig-like domain 2
CSRP2 cysteine and glycine-rich protein 2
EFNB2 ephrin-B2
IGFBP3 insulin-like growth factor binding protein 3
LRRC16A leucine rich repeat containing 16A
MAF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog
NUSAP1 nucleolar and spindle associated protein 1
RRM2 ribonucleotide reductase M2
TFRC transferrin receptor
ZWINT ZW10 interacting kinetochore protein