BRD-A24429032_-666_MCF7_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

68 genes differentially expressed following the BRD-A24429032_-666_MCF7_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ABCB6 ATP-binding cassette, sub-family B (MDR/TAP), member 6 (Langereis blood group)
ABHD4 abhydrolase domain containing 4
AKR1B10 aldo-keto reductase family 1, member B10 (aldose reductase)
AKR1C1 aldo-keto reductase family 1, member C1
AKR1C2 aldo-keto reductase family 1, member C2
AKR1C3 aldo-keto reductase family 1, member C3
ALDH3A1 aldehyde dehydrogenase 3 family, member A1
ALDH3A2 aldehyde dehydrogenase 3 family, member A2
AQP9 aquaporin 9
BCL6 B-cell CLL/lymphoma 6
CAPN2 calpain 2, (m/II) large subunit
CD163 CD163 molecule
CD200 CD200 molecule
CLDN10 claudin 10
FOSL1 FOS-like antigen 1
FST follistatin
G6PD glucose-6-phosphate dehydrogenase
GCLC glutamate-cysteine ligase, catalytic subunit
GCLM glutamate-cysteine ligase, modifier subunit
GULP1 GULP, engulfment adaptor PTB domain containing 1
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
HMOX1 heme oxygenase 1
HSPA1A heat shock 70kDa protein 1A
HSPA6 heat shock 70kDa protein 6 (HSP70B')
IGF2BP3 insulin-like growth factor 2 mRNA binding protein 3
IL1R2 interleukin 1 receptor, type II
IRS2 insulin receptor substrate 2
KCNJ2 potassium channel, inwardly rectifying subfamily J, member 2
LY96 lymphocyte antigen 96
ME1 malic enzyme 1, NADP(+)-dependent, cytosolic
NQO1 NAD(P)H dehydrogenase, quinone 1
NQO2 NAD(P)H dehydrogenase, quinone 2
P3H2 prolyl 3-hydroxylase 2
PGD phosphogluconate dehydrogenase
PLK2 polo-like kinase 2
SLC48A1 solute carrier family 48 (heme transporter), member 1
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
SLC7A7 solute carrier family 7 (amino acid transporter light chain, y+L system), member 7
TMEM158 transmembrane protein 158 (gene/pseudogene)
TRIB3 tribbles pseudokinase 3
TRIM16 tripartite motif containing 16
TXNRD1 thioredoxin reductase 1
WSB1 WD repeat and SOCS box containing 1

decreased expression

Symbol Name
BHLHE41 basic helix-loop-helix family, member e41
CD24 CD24 molecule
CLIC4 chloride intracellular channel 4
CLTC clathrin, heavy chain (Hc)
DEPTOR DEP domain containing MTOR-interacting protein
GPD1L glycerol-3-phosphate dehydrogenase 1-like
GSTM3 glutathione S-transferase mu 3 (brain)
HES1 hes family bHLH transcription factor 1
IGHM immunoglobulin heavy constant mu
KCNK3 potassium channel, two pore domain subfamily K, member 3
KRT7 keratin 7, type II
LGALS3BP lectin, galactoside-binding, soluble, 3 binding protein
LTBP1 latent transforming growth factor beta binding protein 1
LUM lumican
MAP7 microtubule-associated protein 7
MCF2L MCF.2 cell line derived transforming sequence-like
MXRA7 matrix-remodelling associated 7
PCSK1 proprotein convertase subtilisin/kexin type 1
PTCH1 patched 1
REEP1 receptor accessory protein 1
RNF167 ring finger protein 167
SOX4 SRY (sex determining region Y)-box 4
STX1A syntaxin 1A (brain)
TSPAN13 tetraspanin 13