BRD-A24396574_celastrol_MCF10A_3_h_0.37_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

63 genes differentially expressed following the BRD-A24396574_celastrol_MCF10A_3_h_0.37_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
CA12 carbonic anhydrase XII
CD44 CD44 molecule (Indian blood group)
CDA cytidine deaminase
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39)
DAXX death-domain associated protein
DCN decorin
DNAJB1 DnaJ (Hsp40) homolog, subfamily B, member 1
E2F2 E2F transcription factor 2
EFEMP1 EGF containing fibulin-like extracellular matrix protein 1
ESR1 estrogen receptor 1
EVL Enah/Vasp-like
FCGBP Fc fragment of IgG binding protein
FGFR2 fibroblast growth factor receptor 2
GABRE gamma-aminobutyric acid (GABA) A receptor, epsilon
GAL galanin/GMAP prepropeptide
GNG11 guanine nucleotide binding protein (G protein), gamma 11
HMOX1 heme oxygenase 1
HSPA1A heat shock 70kDa protein 1A
HSPA6 heat shock 70kDa protein 6 (HSP70B')
HSPA8 heat shock 70kDa protein 8
IFITM1 interferon induced transmembrane protein 1
IGHMBP2 immunoglobulin mu binding protein 2
MMP10 matrix metallopeptidase 10
RBP4 retinol binding protein 4, plasma
SEPP1 selenoprotein P, plasma, 1
SPRR3 small proline-rich protein 3
TM4SF1 transmembrane 4 L six family member 1
TRPS1 trichorhinophalangeal syndrome I
UCHL1 ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)
VPS28 vacuolar protein sorting 28 homolog (S. cerevisiae)
XIST X inactive specific transcript (non-protein coding)

decreased expression

Symbol Name
ALCAM activated leukocyte cell adhesion molecule
AMD1 adenosylmethionine decarboxylase 1
ANKRD10 ankyrin repeat domain 10
APOD apolipoprotein D
CCNE2 cyclin E2
CD58 CD58 molecule
CDK19 cyclin-dependent kinase 19
CPA3 carboxypeptidase A3 (mast cell)
CSGALNACT1 chondroitin sulfate N-acetylgalactosaminyltransferase 1
DDX3Y DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked
EIF1AY eukaryotic translation initiation factor 1A, Y-linked
FABP7 fatty acid binding protein 7, brain
FAM13A family with sequence similarity 13, member A
FOLH1 folate hydrolase (prostate-specific membrane antigen) 1
GNA15 guanine nucleotide binding protein (G protein), alpha 15 (Gq class)
HIST1H2BG histone cluster 1, H2bg
MEF2C myocyte enhancer factor 2C
MSMB microseminoprotein, beta-
NUPR1 nuclear protein, transcriptional regulator, 1
P4HA1 prolyl 4-hydroxylase, alpha polypeptide I
PLCB1 phospholipase C, beta 1 (phosphoinositide-specific)
PPP3CA protein phosphatase 3, catalytic subunit, alpha isozyme
PSPH phosphoserine phosphatase
REEP1 receptor accessory protein 1
S100P S100 calcium binding protein P
SELL selectin L
SERINC5 serine incorporator 5
SPTSSA serine palmitoyltransferase, small subunit A
TPSAB1 tryptase alpha/beta 1
TPSB2 tryptase beta 2 (gene/pseudogene)
TSPAN8 tetraspanin 8