BRD-A24396574_celastrol_HS578T_3_h_1.11_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
Similar Terms
Downloads & Tools

Genes

82 genes differentially expressed following the BRD-A24396574_celastrol_HS578T_3_h_1.11_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
AMACR alpha-methylacyl-CoA racemase
AQP3 aquaporin 3 (Gill blood group)
ATF3 activating transcription factor 3
BAG3 BCL2-associated athanogene 3
BGN biglycan
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CEACAM5 carcinoembryonic antigen-related cell adhesion molecule 5
CEACAM7 carcinoembryonic antigen-related cell adhesion molecule 7
CEBPA CCAAT/enhancer binding protein (C/EBP), alpha
CLCA1 chloride channel accessory 1
CREM cAMP responsive element modulator
DACH1 dachshund family transcription factor 1
DEFA5 defensin, alpha 5, Paneth cell-specific
DEFA6 defensin, alpha 6, Paneth cell-specific
DNAJB1 DnaJ (Hsp40) homolog, subfamily B, member 1
EGR1 early growth response 1
FABP1 fatty acid binding protein 1, liver
FCMR Fc fragment of IgM receptor
GDF15 growth differentiation factor 15
GLIPR1 GLI pathogenesis-related 1
HMOX1 heme oxygenase 1
HSPA1A heat shock 70kDa protein 1A
HSPA6 heat shock 70kDa protein 6 (HSP70B')
HSPD1 heat shock 60kDa protein 1 (chaperonin)
HSPE1 heat shock 10kDa protein 1
HSPH1 heat shock 105kDa/110kDa protein 1
IGKC immunoglobulin kappa constant
IGKV1-5 immunoglobulin kappa variable 1-5
IGL immunoglobulin lambda locus
IRS2 insulin receptor substrate 2
JMJD6 jumonji domain containing 6
LEF1 lymphoid enhancer-binding factor 1
MMP12 matrix metallopeptidase 12
MMP7 matrix metallopeptidase 7
NEDD9 neural precursor cell expressed, developmentally down-regulated 9
NELL2 NEL-like 2 (chicken)
NR4A1 nuclear receptor subfamily 4, group A, member 1
NRCAM neuronal cell adhesion molecule
PDLIM5 PDZ and LIM domain 5
PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1
REG1A regenerating islet-derived 1 alpha
REG1B regenerating islet-derived 1 beta
REG3A regenerating islet-derived 3 alpha
RGS2 regulator of G-protein signaling 2
S100A10 S100 calcium binding protein A10
SLC1A4 solute carrier family 1 (glutamate/neutral amino acid transporter), member 4
SPR sepiapterin reductase (7,8-dihydrobiopterin:NADP+ oxidoreductase)
SRGN serglycin
TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)
TRBC1 T cell receptor beta constant 1
UGT2B28 UDP glucuronosyltransferase 2 family, polypeptide B28
ZFP36 ZFP36 ring finger protein

decreased expression

Symbol Name
ADIRF adipogenesis regulatory factor
ARPP19 cAMP-regulated phosphoprotein, 19kDa
CA12 carbonic anhydrase XII
CA2 carbonic anhydrase II
CAPN3 calpain 3, (p94)
CCNE2 cyclin E2
CRIP1 cysteine-rich protein 1 (intestinal)
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1
DEPTOR DEP domain containing MTOR-interacting protein
DMXL2 Dmx-like 2
DPT dermatopontin
ENPP2 ectonucleotide pyrophosphatase/phosphodiesterase 2
ENPP4 ectonucleotide pyrophosphatase/phosphodiesterase 4 (putative)
FHL1 four and a half LIM domains 1
GCA grancalcin, EF-hand calcium binding protein
GNAL guanine nucleotide binding protein (G protein), alpha activating activity polypeptide, olfactory type
GPRC5B G protein-coupled receptor, class C, group 5, member B
IGFBP3 insulin-like growth factor binding protein 3
MEIS2 Meis homeobox 2
NCALD neurocalcin delta
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
PLA2G16 phospholipase A2, group XVI
PLN phospholamban
PTGIS prostaglandin I2 (prostacyclin) synthase
RTN1 reticulon 1
TM9SF3 transmembrane 9 superfamily member 3
TXNIP thioredoxin interacting protein
WASF3 WAS protein family, member 3
ZBED2 zinc finger, BED-type containing 2