BRD-A24396574_celastrol_BT20_3_h_10_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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41 genes differentially expressed following the BRD-A24396574_celastrol_BT20_3_h_10_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
AKAP8L A kinase (PRKA) anchor protein 8-like
BASP1 brain abundant, membrane attached signal protein 1
CCL5 chemokine (C-C motif) ligand 5
CD36 CD36 molecule (thrombospondin receptor)
CLGN calmegin
CSTA cystatin A (stefin A)
HOPX HOP homeobox
LMO4 LIM domain only 4
MGLL monoglyceride lipase
PLBD1 phospholipase B domain containing 1
PRAME preferentially expressed antigen in melanoma
SPINK5 serine peptidase inhibitor, Kazal type 5
SPRR1A small proline-rich protein 1A
TFF3 trefoil factor 3 (intestinal)
VIM vimentin

decreased expression

Symbol Name
AHR aryl hydrocarbon receptor
AKAP12 A kinase (PRKA) anchor protein 12
ANXA3 annexin A3
ARPP19 cAMP-regulated phosphoprotein, 19kDa
ATP9A ATPase, class II, type 9A
CALM1 calmodulin 1 (phosphorylase kinase, delta)
CFI complement factor I
CLTC clathrin, heavy chain (Hc)
CPNE3 copine III
CTNND1 catenin (cadherin-associated protein), delta 1
GATA6 GATA binding protein 6
H1F0 H1 histone family, member 0
ITGA6 integrin, alpha 6
NPY1R neuropeptide Y receptor Y1
OSBPL8 oxysterol binding protein-like 8
PDS5A PDS5 cohesin associated factor A
PHLDA1 pleckstrin homology-like domain, family A, member 1
RAB11FIP1 RAB11 family interacting protein 1 (class I)
RAD21 RAD21 homolog (S. pombe)
SORL1 sortilin-related receptor, L(DLR class) A repeats containing
SYT1 synaptotagmin I
TGFBR2 transforming growth factor, beta receptor II (70/80kDa)
TOMM20 translocase of outer mitochondrial membrane 20 homolog (yeast)
TRIB2 tribbles pseudokinase 2
TRIM2 tripartite motif containing 2