BRD-A24381660_zeranol_VCAP_24.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

51 genes differentially expressed following the BRD-A24381660_zeranol_VCAP_24.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ABCC4 ATP-binding cassette, sub-family C (CFTR/MRP), member 4
CLGN calmegin
CSGALNACT1 chondroitin sulfate N-acetylgalactosaminyltransferase 1
DEFB1 defensin, beta 1
DSG2 desmoglein 2
GDF15 growth differentiation factor 15
GLDC glycine dehydrogenase (decarboxylating)
IL6ST interleukin 6 signal transducer
LXN latexin
LY75 lymphocyte antigen 75
NQO1 NAD(P)H dehydrogenase, quinone 1
NT5E 5'-nucleotidase, ecto (CD73)
RAP1GAP RAP1 GTPase activating protein
SFN stratifin
SLC26A2 solute carrier family 26 (anion exchanger), member 2
SLC27A2 solute carrier family 27 (fatty acid transporter), member 2
SLPI secretory leukocyte peptidase inhibitor
SPDEF SAM pointed domain containing ETS transcription factor
VPS28 vacuolar protein sorting 28 homolog (S. cerevisiae)

decreased expression

Symbol Name
ACKR3 atypical chemokine receptor 3
ADH1B alcohol dehydrogenase 1B (class I), beta polypeptide
ATP1B1 ATPase, Na+/K+ transporting, beta 1 polypeptide
AURKB aurora kinase B
CADM1 cell adhesion molecule 1
CD163 CD163 molecule
CD36 CD36 molecule (thrombospondin receptor)
CDO1 cysteine dioxygenase type 1
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39)
CX3CR1 chemokine (C-X3-C motif) receptor 1
DACH1 dachshund family transcription factor 1
DCN decorin
DPYSL3 dihydropyrimidinase-like 3
EFEMP1 EGF containing fibulin-like extracellular matrix protein 1
GNAS GNAS complex locus
IGFBP3 insulin-like growth factor binding protein 3
MARCH6 membrane-associated ring finger (C3HC4) 6, E3 ubiquitin protein ligase
NIT1 nitrilase 1
PEG10 paternally expressed 10
PLEKHM1 pleckstrin homology domain containing, family M (with RUN domain) member 1
PMM2 phosphomannomutase 2
RFTN1 raftlin, lipid raft linker 1
RHOB ras homolog family member B
RTN2 reticulon 2
SCN3A sodium channel, voltage gated, type III alpha subunit
SLN sarcolipin
SNX7 sorting nexin 7
SOX11 SRY (sex determining region Y)-box 11
TMEM176B transmembrane protein 176B
VSIG4 V-set and immunoglobulin domain containing 4