BRD-A24228527_ofloxacin_PC3_24.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
Similar Terms
Downloads & Tools

Genes

39 genes differentially expressed following the BRD-A24228527_ofloxacin_PC3_24.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
AFF1 AF4/FMR2 family, member 1
AGT angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
COBL cordon-bleu WH2 repeat protein
DAPK1 death-associated protein kinase 1
ERAP2 endoplasmic reticulum aminopeptidase 2
HIST1H2BG histone cluster 1, H2bg
PDLIM5 PDZ and LIM domain 5
PENK proenkephalin
PGC progastricsin (pepsinogen C)
RAB2A RAB2A, member RAS oncogene family
TGM2 transglutaminase 2

decreased expression

Symbol Name
AMIGO2 adhesion molecule with Ig-like domain 2
ARHGAP29 Rho GTPase activating protein 29
ASS1 argininosuccinate synthase 1
BCAM basal cell adhesion molecule (Lutheran blood group)
CD24 CD24 molecule
CEP57 centrosomal protein 57kDa
CXCL10 chemokine (C-X-C motif) ligand 10
DNMT3A DNA (cytosine-5-)-methyltransferase 3 alpha
EDN1 endothelin 1
GJA1 gap junction protein, alpha 1, 43kDa
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1
LY96 lymphocyte antigen 96
MN1 meningioma (disrupted in balanced translocation) 1
PAPD7 PAP associated domain containing 7
PAPSS2 3'-phosphoadenosine 5'-phosphosulfate synthase 2
PDZD2 PDZ domain containing 2
PEG10 paternally expressed 10
PFKFB3 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3
PLEKHM1 pleckstrin homology domain containing, family M (with RUN domain) member 1
PRKCI protein kinase C, iota
RAD51AP1 RAD51 associated protein 1
SAMD4A sterile alpha motif domain containing 4A
SLC38A1 solute carrier family 38, member 1
SNX7 sorting nexin 7
TFAP2A transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)
TNS3 tensin 3
ZNF395 zinc finger protein 395