BRD-A24054354_-666_PC3_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

48 genes differentially expressed following the BRD-A24054354_-666_PC3_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
BNIP3 BCL2/adenovirus E1B 19kDa interacting protein 3
CA2 carbonic anhydrase II
CAP2 CAP, adenylate cyclase-associated protein, 2 (yeast)
DMD dystrophin
DNAJA3 DnaJ (Hsp40) homolog, subfamily A, member 3
ENO2 enolase 2 (gamma, neuronal)
GUSBP3 glucuronidase, beta pseudogene 3
HK1 hexokinase 1
HMOX1 heme oxygenase 1
HSPA6 heat shock 70kDa protein 6 (HSP70B')
LDOC1 leucine zipper, down-regulated in cancer 1
MXI1 MAX interactor 1, dimerization protein
NDRG1 N-myc downstream regulated 1
PDLIM5 PDZ and LIM domain 5
SLC35A3 solute carrier family 35 (UDP-N-acetylglucosamine (UDP-GlcNAc) transporter), member A3
TKT transketolase
TMEM158 transmembrane protein 158 (gene/pseudogene)
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10
TPD52L1 tumor protein D52-like 1
ZNF91 zinc finger protein 91

decreased expression

Symbol Name
ACACB acetyl-CoA carboxylase beta
CCL19 chemokine (C-C motif) ligand 19
CCL20 chemokine (C-C motif) ligand 20
CCL21 chemokine (C-C motif) ligand 21
CD24 CD24 molecule
CRISPLD2 cysteine-rich secretory protein LCCL domain containing 2
CTSC cathepsin C
CXCL13 chemokine (C-X-C motif) ligand 13
CXCL2 chemokine (C-X-C motif) ligand 2
EFEMP1 EGF containing fibulin-like extracellular matrix protein 1
G0S2 G0/G1 switch 2
GPM6B glycoprotein M6B
IGHD immunoglobulin heavy constant delta
IGKV4-1 immunoglobulin kappa variable 4-1
IGLJ3 immunoglobulin lambda joining 3
IGLV3-19 immunoglobulin lambda variable 3-19
IL1B interleukin 1, beta
LAMB1 laminin, beta 1
LPL lipoprotein lipase
MARCKS myristoylated alanine-rich protein kinase C substrate
OLFM4 olfactomedin 4
PDCD4 programmed cell death 4 (neoplastic transformation inhibitor)
PEG10 paternally expressed 10
POU2AF1 POU class 2 associating factor 1
PTCH1 patched 1
SPINK1 serine peptidase inhibitor, Kazal type 1
TMEM97 transmembrane protein 97