BRD-A24021119_NCGC00183696-01_HA1E_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

104 genes differentially expressed following the BRD-A24021119_NCGC00183696-01_HA1E_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ACKR3 atypical chemokine receptor 3
ADM adrenomedullin
AK4 adenylate kinase 4
ALDOC aldolase C, fructose-bisphosphate
ANGPTL4 angiopoietin-like 4
APLP1 amyloid beta (A4) precursor-like protein 1
BHLHE40 basic helix-loop-helix family, member e40
BHLHE41 basic helix-loop-helix family, member e41
BNIP3 BCL2/adenovirus E1B 19kDa interacting protein 3
BNIP3L BCL2/adenovirus E1B 19kDa interacting protein 3-like
BTG2 BTG family, member 2
CA9 carbonic anhydrase IX
CASP7 caspase 7, apoptosis-related cysteine peptidase
CCND2 cyclin D2
DDIT4 DNA-damage-inducible transcript 4
EGLN1 egl-9 family hypoxia-inducible factor 1
EGLN3 egl-9 family hypoxia-inducible factor 3
ENO2 enolase 2 (gamma, neuronal)
ENPP4 ectonucleotide pyrophosphatase/phosphodiesterase 4 (putative)
ERO1L ERO1-like (S. cerevisiae)
FAM162A family with sequence similarity 162, member A
FN1 fibronectin 1
GBE1 glucan (1,4-alpha-), branching enzyme 1
GPM6B glycoprotein M6B
HBB hemoglobin, beta
HILPDA hypoxia inducible lipid droplet-associated
HK2 hexokinase 2
IGFBP7 insulin-like growth factor binding protein 7
IRF1 interferon regulatory factor 1
KDM3A lysine (K)-specific demethylase 3A
KRT20 keratin 20, type I
LY75 lymphocyte antigen 75
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
MAP7 microtubule-associated protein 7
MT1M metallothionein 1M
MXI1 MAX interactor 1, dimerization protein
NDRG1 N-myc downstream regulated 1
NDUFA4L2 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 4-like 2
NNMT nicotinamide N-methyltransferase
P2RX5 purinergic receptor P2X, ligand gated ion channel, 5
P4HA1 prolyl 4-hydroxylase, alpha polypeptide I
P4HA2 prolyl 4-hydroxylase, alpha polypeptide II
PFKFB3 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3
PGK1 phosphoglycerate kinase 1
PGM1 phosphoglucomutase 1
PLAGL1 pleiomorphic adenoma gene-like 1
PLIN2 perilipin 2
PLOD2 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2
PRKACB protein kinase, cAMP-dependent, catalytic, beta
PTP4A1 protein tyrosine phosphatase type IVA, member 1
RARRES2 retinoic acid receptor responder (tazarotene induced) 2
RNMT RNA (guanine-7-) methyltransferase
RRAGD Ras-related GTP binding D
S100P S100 calcium binding protein P
SCD stearoyl-CoA desaturase (delta-9-desaturase)
SEL1L3 sel-1 suppressor of lin-12-like 3 (C. elegans)
SLC16A3 solute carrier family 16 (monocarboxylate transporter), member 3
SLC2A3 solute carrier family 2 (facilitated glucose transporter), member 3
SNAP25 synaptosomal-associated protein, 25kDa
SNX10 sorting nexin 10
SPAG4 sperm associated antigen 4
TGFA transforming growth factor, alpha
TNFAIP3 tumor necrosis factor, alpha-induced protein 3
TOB1 transducer of ERBB2, 1
TPD52 tumor protein D52
TXNIP thioredoxin interacting protein
VEGFA vascular endothelial growth factor A
VWF von Willebrand factor
WFDC1 WAP four-disulfide core domain 1
ZNF395 zinc finger protein 395

decreased expression

Symbol Name
AMDHD2 amidohydrolase domain containing 2
AURKA aurora kinase A
BPHL biphenyl hydrolase-like (serine hydrolase)
CCNA2 cyclin A2
CCNF cyclin F
CDC25B cell division cycle 25B
CDCA4 cell division cycle associated 4
CHRDL1 chordin-like 1
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1
DKK1 dickkopf WNT signaling pathway inhibitor 1
GULP1 GULP, engulfment adaptor PTB domain containing 1
H2BFS H2B histone family, member S (pseudogene)
HIST1H1C histone cluster 1, H1c
HIST1H2BD histone cluster 1, H2bd
HIST1H2BK histone cluster 1, H2bk
HOXA5 homeobox A5
HSPA1A heat shock 70kDa protein 1A
ID2 inhibitor of DNA binding 2, dominant negative helix-loop-helix protein
LDOC1 leucine zipper, down-regulated in cancer 1
MAFB v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B
NQO1 NAD(P)H dehydrogenase, quinone 1
NR2F2 nuclear receptor subfamily 2, group F, member 2
S100A4 S100 calcium binding protein A4
SC5D sterol-C5-desaturase
SCAND1 SCAN domain containing 1
SERPINB2 serpin peptidase inhibitor, clade B (ovalbumin), member 2
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
SRC SRC proto-oncogene, non-receptor tyrosine kinase
TBC1D8 TBC1 domain family, member 8 (with GRAM domain)
TFPI2 tissue factor pathway inhibitor 2
TM4SF1 transmembrane 4 L six family member 1
TOP1 topoisomerase (DNA) I
TOP2A topoisomerase (DNA) II alpha 170kDa