BRD-A24021119_NCGC00183696-01_A549_24.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

144 genes differentially expressed following the BRD-A24021119_NCGC00183696-01_A549_24.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCC3 ATP-binding cassette, sub-family C (CFTR/MRP), member 3
ADD3 adducin 3 (gamma)
AGR2 anterior gradient 2
AK4 adenylate kinase 4
ALB albumin
ALCAM activated leukocyte cell adhesion molecule
ALDH6A1 aldehyde dehydrogenase 6 family, member A1
ALDOA aldolase A, fructose-bisphosphate
ALDOC aldolase C, fructose-bisphosphate
ANG angiogenin, ribonuclease, RNase A family, 5
ANKRD10 ankyrin repeat domain 10
APOD apolipoprotein D
ASS1 argininosuccinate synthase 1
ATP9A ATPase, class II, type 9A
BNIP3 BCL2/adenovirus E1B 19kDa interacting protein 3
BNIP3L BCL2/adenovirus E1B 19kDa interacting protein 3-like
C1R complement component 1, r subcomponent
CA9 carbonic anhydrase IX
CD99 CD99 molecule
CERS6 ceramide synthase 6
CITED2 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2
CPE carboxypeptidase E
CST3 cystatin C
CYFIP2 cytoplasmic FMR1 interacting protein 2
DDIT4 DNA-damage-inducible transcript 4
DDX17 DEAD (Asp-Glu-Ala-Asp) box helicase 17
DDX3Y DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked
DHRS3 dehydrogenase/reductase (SDR family) member 3
DUSP6 dual specificity phosphatase 6
EIF1AY eukaryotic translation initiation factor 1A, Y-linked
ENO2 enolase 2 (gamma, neuronal)
ERAP2 endoplasmic reticulum aminopeptidase 2
ERP29 endoplasmic reticulum protein 29
FAM13A family with sequence similarity 13, member A
FAM162A family with sequence similarity 162, member A
GALNT12 polypeptide N-acetylgalactosaminyltransferase 12
GATA6 GATA binding protein 6
GBE1 glucan (1,4-alpha-), branching enzyme 1
GPI glucose-6-phosphate isomerase
GPX2 glutathione peroxidase 2
GRB10 growth factor receptor-bound protein 10
GSTK1 glutathione S-transferase kappa 1
GSTM3 glutathione S-transferase mu 3 (brain)
GUSB glucuronidase, beta
HERC6 HECT and RLD domain containing E3 ubiquitin protein ligase family member 6
HILPDA hypoxia inducible lipid droplet-associated
HK2 hexokinase 2
HPCAL1 hippocalcin-like 1
HSD17B11 hydroxysteroid (17-beta) dehydrogenase 11
IFI44L interferon-induced protein 44-like
IFITM1 interferon induced transmembrane protein 1
IFITM2 interferon induced transmembrane protein 2
IGFBP2 insulin-like growth factor binding protein 2, 36kDa
IGFBP3 insulin-like growth factor binding protein 3
IGFBP5 insulin-like growth factor binding protein 5
ITGBL1 integrin, beta-like 1 (with EGF-like repeat domains)
JUN jun proto-oncogene
KCNJ2 potassium channel, inwardly rectifying subfamily J, member 2
KDM3A lysine (K)-specific demethylase 3A
KDM5D lysine (K)-specific demethylase 5D
LDOC1 leucine zipper, down-regulated in cancer 1
LOX lysyl oxidase
NDRG1 N-myc downstream regulated 1
NMU neuromedin U
NPTX2 neuronal pentraxin II
NRCAM neuronal cell adhesion molecule
NRN1 neuritin 1
NUPR1 nuclear protein, transcriptional regulator, 1
ORAI3 ORAI calcium release-activated calcium modulator 3
P4HA1 prolyl 4-hydroxylase, alpha polypeptide I
P4HA2 prolyl 4-hydroxylase, alpha polypeptide II
PDGFC platelet derived growth factor C
PDIA3 protein disulfide isomerase family A, member 3
PDK1 pyruvate dehydrogenase kinase, isozyme 1
PFKL phosphofructokinase, liver
PGK1 phosphoglycerate kinase 1
PLAGL1 pleiomorphic adenoma gene-like 1
PLOD2 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2
RAB31 RAB31, member RAS oncogene family
RAP1GAP RAP1 GTPase activating protein
RBP4 retinol binding protein 4, plasma
RNASE4 ribonuclease, RNase A family, 4
RNASET2 ribonuclease T2
SKAP2 src kinase associated phosphoprotein 2
SLC16A3 solute carrier family 16 (monocarboxylate transporter), member 3
SLC22A18 solute carrier family 22, member 18
SLC6A8 solute carrier family 6 (neurotransmitter transporter), member 8
SPAG4 sperm associated antigen 4
STC1 stanniocalcin 1
STC2 stanniocalcin 2
SULT1A1 sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1
SYBU syntabulin (syntaxin-interacting)
TCAF1 TRPM8 channel-associated factor 1
TF transferrin
TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)
TGFBI transforming growth factor, beta-induced, 68kDa
TNIP1 TNFAIP3 interacting protein 1
TP53 tumor protein p53
TP53TG1 TP53 target 1 (non-protein coding)
TRAPPC6A trafficking protein particle complex 6A
TSC22D3 TSC22 domain family, member 3
TSPAN31 tetraspanin 31
TTC3 tetratricopeptide repeat domain 3
TXNIP thioredoxin interacting protein
VEGFA vascular endothelial growth factor A
VGLL4 vestigial-like family member 4
ZMAT3 zinc finger, matrin-type 3
ZNF91 zinc finger protein 91

decreased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ANP32E acidic (leucine-rich) nuclear phosphoprotein 32 family, member E
ARMCX2 armadillo repeat containing, X-linked 2
ATP6V1D ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D
CCND3 cyclin D3
CHORDC1 cysteine and histidine-rich domain (CHORD) containing 1
CLNS1A chloride channel, nucleotide-sensitive, 1A
COL15A1 collagen, type XV, alpha 1
COL3A1 collagen, type III, alpha 1
CRIP1 cysteine-rich protein 1 (intestinal)
CRY1 cryptochrome circadian clock 1
DIMT1 DIM1 dimethyladenosine transferase 1 homolog (S. cerevisiae)
FABP4 fatty acid binding protein 4, adipocyte
FASTKD5 FAST kinase domains 5
GRWD1 glutamate-rich WD repeat containing 1
HES1 hes family bHLH transcription factor 1
HMGB3 high mobility group box 3
HSPA1A heat shock 70kDa protein 1A
HSPH1 heat shock 105kDa/110kDa protein 1
HTATIP2 HIV-1 Tat interactive protein 2, 30kDa
ID2 inhibitor of DNA binding 2, dominant negative helix-loop-helix protein
KRT14 keratin 14, type I
MARCKS myristoylated alanine-rich protein kinase C substrate
NOLC1 nucleolar and coiled-body phosphoprotein 1
NOP16 NOP16 nucleolar protein
RGCC regulator of cell cycle
RPL39L ribosomal protein L39-like
RRP15 ribosomal RNA processing 15 homolog (S. cerevisiae)
RRP1B ribosomal RNA processing 1B
SGK1 serum/glucocorticoid regulated kinase 1
SPON1 spondin 1, extracellular matrix protein
TACSTD2 tumor-associated calcium signal transducer 2
TCF4 transcription factor 4
TIMM17A translocase of inner mitochondrial membrane 17 homolog A (yeast)
WDR12 WD repeat domain 12
XIST X inactive specific transcript (non-protein coding)