BRD-A23723433_Taxol_PC3_24.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

74 genes differentially expressed following the BRD-A23723433_Taxol_PC3_24.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
BCAT1 branched chain amino-acid transaminase 1, cytosolic
C6ORF62 chromosome 6 open reading frame 62
CAV1 caveolin 1, caveolae protein, 22kDa
CAV2 caveolin 2
CX3CR1 chemokine (C-X3-C motif) receptor 1
CXCL2 chemokine (C-X-C motif) ligand 2
CXCL3 chemokine (C-X-C motif) ligand 3
DDIT4 DNA-damage-inducible transcript 4
HIC2 hypermethylated in cancer 2
HIST1H2AC histone cluster 1, H2ac
HIST1H2BD histone cluster 1, H2bd
HIST1H2BG histone cluster 1, H2bg
HIST1H2BK histone cluster 1, H2bk
HIST2H2BE histone cluster 2, H2be
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1
KIAA0226L KIAA0226-like
KLF4 Kruppel-like factor 4 (gut)
KRT14 keratin 14, type I
MT1M metallothionein 1M
NUCB2 nucleobindin 2
PFKFB3 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3
PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1
PTPRK protein tyrosine phosphatase, receptor type, K
RGS1 regulator of G-protein signaling 1
SAT1 spermidine/spermine N1-acetyltransferase 1
SEMA6A sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
TXNIP thioredoxin interacting protein

decreased expression

Symbol Name
ABCB6 ATP-binding cassette, sub-family B (MDR/TAP), member 6 (Langereis blood group)
AKR1B10 aldo-keto reductase family 1, member B10 (aldose reductase)
ANK3 ankyrin 3, node of Ranvier (ankyrin G)
ASPH aspartate beta-hydroxylase
AURKB aurora kinase B
BLMH bleomycin hydrolase
C1S complement component 1, s subcomponent
CCNF cyclin F
CDK1 cyclin-dependent kinase 1
CHEK2 checkpoint kinase 2
COL6A1 collagen, type VI, alpha 1
COL6A3 collagen, type VI, alpha 3
COPS7A COP9 signalosome subunit 7A
DTL denticleless E3 ubiquitin protein ligase homolog (Drosophila)
ENO2 enolase 2 (gamma, neuronal)
ETV1 ets variant 1
HMGA2 high mobility group AT-hook 2
HOXC10 homeobox C10
HOXC6 homeobox C6
HSPA1A heat shock 70kDa protein 1A
IMPA2 inositol(myo)-1(or 4)-monophosphatase 2
KDM5D lysine (K)-specific demethylase 5D
KIAA0101 KIAA0101
MCM2 minichromosome maintenance complex component 2
MCM5 minichromosome maintenance complex component 5
MCM6 minichromosome maintenance complex component 6
MCM7 minichromosome maintenance complex component 7
MGP matrix Gla protein
MLLT11 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11
MSH6 mutS homolog 6
MSL1 male-specific lethal 1 homolog (Drosophila)
NREP neuronal regeneration related protein
RFC2 replication factor C (activator 1) 2, 40kDa
RGS4 regulator of G-protein signaling 4
RNF128 ring finger protein 128, E3 ubiquitin protein ligase
RPS4Y1 ribosomal protein S4, Y-linked 1
SVIL supervillin
THBS2 thrombospondin 2
TMEM45A transmembrane protein 45A
TOMM70A translocase of outer mitochondrial membrane 70 homolog A (S. cerevisiae)
TOP2A topoisomerase (DNA) II alpha 170kDa
TOPBP1 topoisomerase (DNA) II binding protein 1
UBE2A ubiquitin-conjugating enzyme E2A
UBE2C ubiquitin-conjugating enzyme E2C
ZWINT ZW10 interacting kinetochore protein