BRD-A23723433_-666_NPC_24.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

76 genes differentially expressed following the BRD-A23723433_-666_NPC_24.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
AUTS2 autism susceptibility candidate 2
CA12 carbonic anhydrase XII
CD44 CD44 molecule (Indian blood group)
CDC20 cell division cycle 20
CEACAM6 carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen)
CLEC2B C-type lectin domain family 2, member B
COL4A6 collagen, type IV, alpha 6
CRYM crystallin, mu
CTSD cathepsin D
EDNRA endothelin receptor type A
ENPP1 ectonucleotide pyrophosphatase/phosphodiesterase 1
ESR1 estrogen receptor 1
FAM69A family with sequence similarity 69, member A
GNAQ guanine nucleotide binding protein (G protein), q polypeptide
GUSBP3 glucuronidase, beta pseudogene 3
HIST1H2BG histone cluster 1, H2bg
HSD17B6 hydroxysteroid (17-beta) dehydrogenase 6
INSM1 insulinoma-associated 1
ITGB4 integrin, beta 4
KIF14 kinesin family member 14
KIF20A kinesin family member 20A
NVL nuclear VCP-like
PDLIM3 PDZ and LIM domain 3
PLA2G4A phospholipase A2, group IVA (cytosolic, calcium-dependent)
PLK1 polo-like kinase 1
PON3 paraoxonase 3
PPAP2A phosphatidic acid phosphatase type 2A
PRTN3 proteinase 3
PSRC1 proline/serine-rich coiled-coil 1
PXN paxillin
SMYD3 SET and MYND domain containing 3
SNAI2 snail family zinc finger 2
STC1 stanniocalcin 1
TARP TCR gamma alternate reading frame protein
TMEM158 transmembrane protein 158 (gene/pseudogene)
TNFRSF21 tumor necrosis factor receptor superfamily, member 21
XIST X inactive specific transcript (non-protein coding)

decreased expression

Symbol Name
AKR1B1 aldo-keto reductase family 1, member B1 (aldose reductase)
ASPH aspartate beta-hydroxylase
BST2 bone marrow stromal cell antigen 2
CDKN1C cyclin-dependent kinase inhibitor 1C (p57, Kip2)
CLU clusterin
CTGF connective tissue growth factor
CXCL12 chemokine (C-X-C motif) ligand 12
CYR61 cysteine-rich, angiogenic inducer, 61
DDX3Y DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked
EGR3 early growth response 3
EIF1AY eukaryotic translation initiation factor 1A, Y-linked
EIF5A eukaryotic translation initiation factor 5A
GLS glutaminase
GOLGA7 golgin A7
GOLT1B golgi transport 1B
GSTM3 glutathione S-transferase mu 3 (brain)
IGFBP3 insulin-like growth factor binding protein 3
ITGAV integrin, alpha V
KDM5D lysine (K)-specific demethylase 5D
LDHB lactate dehydrogenase B
LRP4 low density lipoprotein receptor-related protein 4
MAGEA3 melanoma antigen family A3
MAGEA6 melanoma antigen family A6
NQO1 NAD(P)H dehydrogenase, quinone 1
NTRK2 neurotrophic tyrosine kinase, receptor, type 2
PALLD palladin, cytoskeletal associated protein
PHLDA1 pleckstrin homology-like domain, family A, member 1
PRDX2 peroxiredoxin 2
RPS4Y1 ribosomal protein S4, Y-linked 1
SACS sacsin molecular chaperone
SCAND1 SCAN domain containing 1
SFRP1 secreted frizzled-related protein 1
SMCO4 single-pass membrane protein with coiled-coil domains 4
SYNM synemin, intermediate filament protein
TAF1D TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa
TBC1D4 TBC1 domain family, member 4
TCN1 transcobalamin I (vitamin B12 binding protein, R binder family)
TNFRSF10B tumor necrosis factor receptor superfamily, member 10b