BRD-A23723433_-666_MCF7_24.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
Similar Terms
Downloads & Tools

Genes

144 genes differentially expressed following the BRD-A23723433_-666_MCF7_24.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ABCC4 ATP-binding cassette, sub-family C (CFTR/MRP), member 4
ACTA1 actin, alpha 1, skeletal muscle
AGRN agrin
ALDH5A1 aldehyde dehydrogenase 5 family, member A1
ALOX5 arachidonate 5-lipoxygenase
ANKMY2 ankyrin repeat and MYND domain containing 2
ARHGDIB Rho GDP dissociation inhibitor (GDI) beta
ATP5H ATP synthase, H+ transporting, mitochondrial Fo complex, subunit d
CAST calpastatin
CAV1 caveolin 1, caveolae protein, 22kDa
CAV2 caveolin 2
CD40 CD40 molecule, TNF receptor superfamily member 5
CD9 CD9 molecule
CLC Charcot-Leyden crystal galectin
CPA3 carboxypeptidase A3 (mast cell)
CRIM1 cysteine rich transmembrane BMP regulator 1 (chordin-like)
CSRP2 cysteine and glycine-rich protein 2
CTGF connective tissue growth factor
CYR61 cysteine-rich, angiogenic inducer, 61
CYTIP cytohesin 1 interacting protein
DEFA4 defensin, alpha 4, corticostatin
DHCR24 24-dehydrocholesterol reductase
DLK1 delta-like 1 homolog (Drosophila)
DPYSL3 dihydropyrimidinase-like 3
ELANE elastase, neutrophil expressed
EPAS1 endothelial PAS domain protein 1
EREG epiregulin
FABP4 fatty acid binding protein 4, adipocyte
FAM129A family with sequence similarity 129, member A
FGFR2 fibroblast growth factor receptor 2
FN1 fibronectin 1
FSTL1 follistatin-like 1
GABBR2 gamma-aminobutyric acid (GABA) B receptor, 2
GABRE gamma-aminobutyric acid (GABA) A receptor, epsilon
HIST1H1C histone cluster 1, H1c
HIST1H2AC histone cluster 1, H2ac
HIST2H2BE histone cluster 2, H2be
IGHM immunoglobulin heavy constant mu
IGLV3-19 immunoglobulin lambda variable 3-19
JUP junction plakoglobin
LYPD1 LY6/PLAUR domain containing 1
MAGEA3 melanoma antigen family A3
MAGEA6 melanoma antigen family A6
MS4A3 membrane-spanning 4-domains, subfamily A, member 3 (hematopoietic cell-specific)
MSN moesin
MT1E metallothionein 1E
NEB nebulin
NELL2 NEL-like 2 (chicken)
NMU neuromedin U
NNMT nicotinamide N-methyltransferase
PCLO piccolo presynaptic cytomatrix protein
PRG2 proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein)
RFTN1 raftlin, lipid raft linker 1
RGCC regulator of cell cycle
RGS1 regulator of G-protein signaling 1
RPS6KA2 ribosomal protein S6 kinase, 90kDa, polypeptide 2
SDC3 syndecan 3
SH2B3 SH2B adaptor protein 3
TCL1A T-cell leukemia/lymphoma 1A
TGFB1 transforming growth factor, beta 1
TIMP1 TIMP metallopeptidase inhibitor 1
TNFRSF21 tumor necrosis factor receptor superfamily, member 21
TPM1 tropomyosin 1 (alpha)
TPSAB1 tryptase alpha/beta 1
TPSB2 tryptase beta 2 (gene/pseudogene)
TRHDE thyrotropin-releasing hormone degrading enzyme
TUBB6 tubulin, beta 6 class V
VAMP1 vesicle-associated membrane protein 1 (synaptobrevin 1)
VEGFA vascular endothelial growth factor A
ZMYND8 zinc finger, MYND-type containing 8
ZNF91 zinc finger protein 91

decreased expression

Symbol Name
AK4 adenylate kinase 4
AKR1B10 aldo-keto reductase family 1, member B10 (aldose reductase)
AKR1C3 aldo-keto reductase family 1, member C3
AKR7A2 aldo-keto reductase family 7, member A2 (aflatoxin aldehyde reductase)
ARCN1 archain 1
ATP6V1A ATPase, H+ transporting, lysosomal 70kDa, V1 subunit A
B4GALT5 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5
BNIP3 BCL2/adenovirus E1B 19kDa interacting protein 3
CDK1 cyclin-dependent kinase 1
CDKN1C cyclin-dependent kinase inhibitor 1C (p57, Kip2)
CELF2 CUGBP, Elav-like family member 2
CHEK2 checkpoint kinase 2
CLTC clathrin, heavy chain (Hc)
CPS1 carbamoyl-phosphate synthase 1, mitochondrial
CRTAP cartilage associated protein
CRYL1 crystallin, lambda 1
CXCL12 chemokine (C-X-C motif) ligand 12
CYB5A cytochrome b5 type A (microsomal)
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1
DNAJB1 DnaJ (Hsp40) homolog, subfamily B, member 1
DNAJC12 DnaJ (Hsp40) homolog, subfamily C, member 12
DTL denticleless E3 ubiquitin protein ligase homolog (Drosophila)
EED embryonic ectoderm development
ESR1 estrogen receptor 1
FAM57A family with sequence similarity 57, member A
FEN1 flap structure-specific endonuclease 1
FIS1 fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae)
FXYD3 FXYD domain containing ion transport regulator 3
G3BP1 GTPase activating protein (SH3 domain) binding protein 1
GATA3 GATA binding protein 3
GNPDA1 glucosamine-6-phosphate deaminase 1
GOLGA7 golgin A7
H2AFX H2A histone family, member X
HADH hydroxyacyl-CoA dehydrogenase
KAT6A K(lysine) acetyltransferase 6A
KDELR3 KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 3
KIAA0101 KIAA0101
MAFB v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B
MAP2K6 mitogen-activated protein kinase kinase 6
MBP myelin basic protein
MKI67 marker of proliferation Ki-67
MSH6 mutS homolog 6
MTHFD2 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase
NET1 neuroepithelial cell transforming 1
NOLC1 nucleolar and coiled-body phosphoprotein 1
NRIP1 nuclear receptor interacting protein 1
PCNA proliferating cell nuclear antigen
PPIF peptidylprolyl isomerase F
PRKCD protein kinase C, delta
PTGES prostaglandin E synthase
QDPR quinoid dihydropteridine reductase
RAB31 RAB31, member RAS oncogene family
RNASE4 ribonuclease, RNase A family, 4
RNMT RNA (guanine-7-) methyltransferase
RRM1 ribonucleotide reductase M1
SEPP1 selenoprotein P, plasma, 1
SLC5A6 solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6
SLC7A1 solute carrier family 7 (cationic amino acid transporter, y+ system), member 1
SPG21 spastic paraplegia 21 (autosomal recessive, Mast syndrome)
SRPRB signal recognition particle receptor, B subunit
SRSF7 serine/arginine-rich splicing factor 7
TFF1 trefoil factor 1
TFF3 trefoil factor 3 (intestinal)
TM9SF2 transmembrane 9 superfamily member 2
TMED10 transmembrane emp24-like trafficking protein 10 (yeast)
TOMM70A translocase of outer mitochondrial membrane 70 homolog A (S. cerevisiae)
TOP2A topoisomerase (DNA) II alpha 170kDa
TYMS thymidylate synthetase
UBE2A ubiquitin-conjugating enzyme E2A
UBE2C ubiquitin-conjugating enzyme E2C
UCP2 uncoupling protein 2 (mitochondrial, proton carrier)
USP1 ubiquitin specific peptidase 1