BRD-A23689620_Avermectin B1a_MCF7_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

84 genes differentially expressed following the BRD-A23689620_Avermectin B1a_MCF7_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ANXA1 annexin A1
ASNS asparagine synthetase (glutamine-hydrolyzing)
ATF3 activating transcription factor 3
CCND2 cyclin D2
CFD complement factor D (adipsin)
COLEC12 collectin sub-family member 12
CWC25 CWC25 spliceosome-associated protein homolog (S. cerevisiae)
DDIT4 DNA-damage-inducible transcript 4
EFHD1 EF-hand domain family, member D1
EPB41L2 erythrocyte membrane protein band 4.1-like 2
FCGBP Fc fragment of IgG binding protein
FN1 fibronectin 1
HIST1H1C histone cluster 1, H1c
HIST1H2AC histone cluster 1, H2ac
HIST1H2BD histone cluster 1, H2bd
HMOX1 heme oxygenase 1
ID4 inhibitor of DNA binding 4, dominant negative helix-loop-helix protein
IGFBP5 insulin-like growth factor binding protein 5
LASP1 LIM and SH3 protein 1
LCN2 lipocalin 2
LMO4 LIM domain only 4
MAPKAPK5 mitogen-activated protein kinase-activated protein kinase 5
MARS methionyl-tRNA synthetase
NEAT1 nuclear paraspeckle assembly transcript 1 (non-protein coding)
NFIL3 nuclear factor, interleukin 3 regulated
NFKBIB nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta
NID2 nidogen 2 (osteonidogen)
NUPR1 nuclear protein, transcriptional regulator, 1
OLFM4 olfactomedin 4
PCGF2 polycomb group ring finger 2
PCK2 phosphoenolpyruvate carboxykinase 2 (mitochondrial)
PDGFRA platelet-derived growth factor receptor, alpha polypeptide
PDZRN3 PDZ domain containing ring finger 3
PEG10 paternally expressed 10
PROM1 prominin 1
PROS1 protein S (alpha)
PSMB3 proteasome (prosome, macropain) subunit, beta type, 3
PTX3 pentraxin 3, long
RPS4Y1 ribosomal protein S4, Y-linked 1
RSL24D1 ribosomal L24 domain containing 1
S100A1 S100 calcium binding protein A1
S100P S100 calcium binding protein P
SDC2 syndecan 2
SERPINA3 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3
SGCE sarcoglycan, epsilon
SNAI2 snail family zinc finger 2
STAR steroidogenic acute regulatory protein
TMEM100 transmembrane protein 100
TPD52 tumor protein D52
UBQLN2 ubiquilin 2
UFM1 ubiquitin-fold modifier 1
VEGFA vascular endothelial growth factor A

decreased expression

Symbol Name
AKR1C1 aldo-keto reductase family 1, member C1
AKR1C2 aldo-keto reductase family 1, member C2
ATP6V0E2 ATPase, H+ transporting V0 subunit e2
BCL6 B-cell CLL/lymphoma 6
BST2 bone marrow stromal cell antigen 2
CA12 carbonic anhydrase XII
CA2 carbonic anhydrase II
CYB561 cytochrome b561
CYFIP2 cytoplasmic FMR1 interacting protein 2
DEFB1 defensin, beta 1
DLD dihydrolipoamide dehydrogenase
ENPP2 ectonucleotide pyrophosphatase/phosphodiesterase 2
GAL galanin/GMAP prepropeptide
GATA3 GATA binding protein 3
HSPA1A heat shock 70kDa protein 1A
KRT14 keratin 14, type I
KRT5 keratin 5, type II
LGALS3BP lectin, galactoside-binding, soluble, 3 binding protein
MALT1 MALT1 paracaspase
P4HTM prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum)
PDGFA platelet-derived growth factor alpha polypeptide
PPIG peptidylprolyl isomerase G (cyclophilin G)
PRDX2 peroxiredoxin 2
PXDN peroxidasin
SFN stratifin
SNCA synuclein, alpha (non A4 component of amyloid precursor)
SPRR1A small proline-rich protein 1A
TFPI2 tissue factor pathway inhibitor 2
TNIP1 TNFAIP3 interacting protein 1
TRIP6 thyroid hormone receptor interactor 6
XIST X inactive specific transcript (non-protein coding)