BRD-A23290232_westcort_VCAP_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

35 genes differentially expressed following the BRD-A23290232_westcort_VCAP_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AGTR1 angiotensin II receptor, type 1
ANKRD10 ankyrin repeat domain 10
ASAH1 N-acylsphingosine amidohydrolase (acid ceramidase) 1
ATMIN ATM interactor
CCND1 cyclin D1
DSP desmoplakin
FGG fibrinogen gamma chain
HACD2 3-hydroxyacyl-CoA dehydratase 2
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
IDI1 isopentenyl-diphosphate delta isomerase 1
INSIG1 insulin induced gene 1
ITGA6 integrin, alpha 6
ITM2A integral membrane protein 2A
KRT14 keratin 14, type I
KRT5 keratin 5, type II
LYPLA1 lysophospholipase I
MAGEA3 melanoma antigen family A3
MAGEA6 melanoma antigen family A6
ME1 malic enzyme 1, NADP(+)-dependent, cytosolic
MSMO1 methylsterol monooxygenase 1
NRIP1 nuclear receptor interacting protein 1
S100A14 S100 calcium binding protein A14
SRSF11 serine/arginine-rich splicing factor 11
TIMP3 TIMP metallopeptidase inhibitor 3
TNFAIP3 tumor necrosis factor, alpha-induced protein 3
TSPAN13 tetraspanin 13

decreased expression

Symbol Name
AQP1 aquaporin 1 (Colton blood group)
BMP4 bone morphogenetic protein 4
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group)
CNPY3 canopy FGF signaling regulator 3
IGFBP2 insulin-like growth factor binding protein 2, 36kDa
NEFH neurofilament, heavy polypeptide
REC8 REC8 meiotic recombination protein
RGCC regulator of cell cycle
TMEM158 transmembrane protein 158 (gene/pseudogene)