BRD-A23072235_PHENIRAMINE MALEATE_VCAP_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

56 genes differentially expressed following the BRD-A23072235_PHENIRAMINE MALEATE_VCAP_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ALDH1A3 aldehyde dehydrogenase 1 family, member A3
ANPEP alanyl (membrane) aminopeptidase
CXCL13 chemokine (C-X-C motif) ligand 13
CYTH1 cytohesin 1
DHRS3 dehydrogenase/reductase (SDR family) member 3
EDEM1 ER degradation enhancer, mannosidase alpha-like 1
FOXO3 forkhead box O3
GDPD5 glycerophosphodiester phosphodiesterase domain containing 5
GLRX glutaredoxin (thioltransferase)
GLUL glutamate-ammonia ligase
HOMER2 homer scaffolding protein 2
IFI27 interferon, alpha-inducible protein 27
LTF lactotransferrin
MMP9 matrix metallopeptidase 9
NELL2 NEL-like 2 (chicken)
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
NID1 nidogen 1
PCDH7 protocadherin 7
PLCB1 phospholipase C, beta 1 (phosphoinositide-specific)
RGCC regulator of cell cycle
SERPINA3 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3
SNCA synuclein, alpha (non A4 component of amyloid precursor)
SPDEF SAM pointed domain containing ETS transcription factor
STC1 stanniocalcin 1
TCF4 transcription factor 4
TFPI2 tissue factor pathway inhibitor 2
TIPARP TCDD-inducible poly(ADP-ribose) polymerase

decreased expression

Symbol Name
ADD3 adducin 3 (gamma)
ADGRE5 adhesion G protein-coupled receptor E5
ATP6V0E1 ATPase, H+ transporting, lysosomal 9kDa, V0 subunit e1
CCND2 cyclin D2
COL16A1 collagen, type XVI, alpha 1
CX3CR1 chemokine (C-X3-C motif) receptor 1
ETS2 v-ets avian erythroblastosis virus E26 oncogene homolog 2
GRWD1 glutamate-rich WD repeat containing 1
HOPX HOP homeobox
HOXC6 homeobox C6
IGFBP3 insulin-like growth factor binding protein 3
IL1RN interleukin 1 receptor antagonist
KLHL21 kelch-like family member 21
LAMP5 lysosomal-associated membrane protein family, member 5
MEIS1 Meis homeobox 1
MFAP5 microfibrillar associated protein 5
MYC v-myc avian myelocytomatosis viral oncogene homolog
NOP16 NOP16 nucleolar protein
NREP neuronal regeneration related protein
PDZD8 PDZ domain containing 8
PPIF peptidylprolyl isomerase F
PTP4A1 protein tyrosine phosphatase type IVA, member 1
RPL37A ribosomal protein L37a
SLC27A2 solute carrier family 27 (fatty acid transporter), member 2
STEAP1 six transmembrane epithelial antigen of the prostate 1
TIMP3 TIMP metallopeptidase inhibitor 3
TLE1 transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila)
TSPAN8 tetraspanin 8