BRD-A22783572_-666_A375_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

17 genes differentially expressed following the BRD-A22783572_-666_A375_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ANO1 anoctamin 1, calcium activated chloride channel
ASS1 argininosuccinate synthase 1
ATP1B1 ATPase, Na+/K+ transporting, beta 1 polypeptide
DHRS2 dehydrogenase/reductase (SDR family) member 2
DLK1 delta-like 1 homolog (Drosophila)
FHL2 four and a half LIM domains 2
IGFBP5 insulin-like growth factor binding protein 5
JUN jun proto-oncogene
KLF6 Kruppel-like factor 6
PEG3 paternally expressed 3
SCRG1 stimulator of chondrogenesis 1
TTC39A tetratricopeptide repeat domain 39A

decreased expression

Symbol Name
DDIT4 DNA-damage-inducible transcript 4
DUSP6 dual specificity phosphatase 6
IER3 immediate early response 3
S100A10 S100 calcium binding protein A10
TCN1 transcobalamin I (vitamin B12 binding protein, R binder family)