BRD-A22707317_-666_A549_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
Similar Terms
Downloads & Tools

Genes

125 genes differentially expressed following the BRD-A22707317_-666_A549_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
AHNAK2 AHNAK nucleoprotein 2
ARL6IP5 ADP-ribosylation factor-like 6 interacting protein 5
BBOX1 butyrobetaine (gamma), 2-oxoglutarate dioxygenase (gamma-butyrobetaine hydroxylase) 1
BCL6 B-cell CLL/lymphoma 6
CD59 CD59 molecule, complement regulatory protein
CEBPD CCAAT/enhancer binding protein (C/EBP), delta
CPM carboxypeptidase M
DDIT4 DNA-damage-inducible transcript 4
DUSP1 dual specificity phosphatase 1
EMP1 epithelial membrane protein 1
F3 coagulation factor III (thromboplastin, tissue factor)
FKBP5 FK506 binding protein 5
GADD45A growth arrest and DNA-damage-inducible, alpha
GADD45B growth arrest and DNA-damage-inducible, beta
GLRX glutaredoxin (thioltransferase)
GLUL glutamate-ammonia ligase
IFITM1 interferon induced transmembrane protein 1
IFITM3 interferon induced transmembrane protein 3
IL1R2 interleukin 1 receptor, type II
KLF9 Kruppel-like factor 9
LAMP5 lysosomal-associated membrane protein family, member 5
MAOA monoamine oxidase A
MAPT microtubule-associated protein tau
MBD2 methyl-CpG binding domain protein 2
MCL1 myeloid cell leukemia 1
METTL7A methyltransferase like 7A
MFAP5 microfibrillar associated protein 5
MKNK2 MAP kinase interacting serine/threonine kinase 2
NEFL neurofilament, light polypeptide
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
NNMT nicotinamide N-methyltransferase
NOL3 nucleolar protein 3 (apoptosis repressor with CARD domain)
PAM peptidylglycine alpha-amidating monooxygenase
PDLIM1 PDZ and LIM domain 1
PEG10 paternally expressed 10
PER1 period circadian clock 1
PGC progastricsin (pepsinogen C)
PRKCD protein kinase C, delta
PTPRO protein tyrosine phosphatase, receptor type, O
RGS1 regulator of G-protein signaling 1
RGS2 regulator of G-protein signaling 2
S100A2 S100 calcium binding protein A2
S100A8 S100 calcium binding protein A8
SAP30 Sin3A-associated protein, 30kDa
SDC1 syndecan 1
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
SFTPA2 surfactant protein A2
SV2C synaptic vesicle glycoprotein 2C
TLR4 toll-like receptor 4
TSC22D3 TSC22 domain family, member 3
TSPAN13 tetraspanin 13
TXNDC9 thioredoxin domain containing 9
TXNIP thioredoxin interacting protein
UBE3B ubiquitin protein ligase E3B
VCAN versican
ZBTB16 zinc finger and BTB domain containing 16
ZFP36 ZFP36 ring finger protein
ZW10 zw10 kinetochore protein

decreased expression

Symbol Name
ADCK3 aarF domain containing kinase 3
ANXA3 annexin A3
APOBEC3B apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3B
ASNS asparagine synthetase (glutamine-hydrolyzing)
BIRC3 baculoviral IAP repeat containing 3
BMP2 bone morphogenetic protein 2
C2CD2 C2 calcium-dependent domain containing 2
CA2 carbonic anhydrase II
CCL2 chemokine (C-C motif) ligand 2
CCL20 chemokine (C-C motif) ligand 20
CCL5 chemokine (C-C motif) ligand 5
CEACAM5 carcinoembryonic antigen-related cell adhesion molecule 5
CHMP4A charged multivesicular body protein 4A
CKM creatine kinase, muscle
CLU clusterin
CPB1 carboxypeptidase B1 (tissue)
CXCL1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)
CXCL10 chemokine (C-X-C motif) ligand 10
CXCL11 chemokine (C-X-C motif) ligand 11
CXCL8 chemokine (C-X-C motif) ligand 8
DUSP4 dual specificity phosphatase 4
EPHA2 EPH receptor A2
FLRT2 fibronectin leucine rich transmembrane protein 2
FOSL1 FOS-like antigen 1
FZD7 frizzled class receptor 7
GDF15 growth differentiation factor 15
GPRC5B G protein-coupled receptor, class C, group 5, member B
HHEX hematopoietically expressed homeobox
HMG20B high mobility group 20B
HMOX1 heme oxygenase 1
HSPA1A heat shock 70kDa protein 1A
ID1 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein
ID3 inhibitor of DNA binding 3, dominant negative helix-loop-helix protein
IER3 immediate early response 3
IGFBP3 insulin-like growth factor binding protein 3
IGHM immunoglobulin heavy constant mu
IKZF1 IKAROS family zinc finger 1 (Ikaros)
IL32 interleukin 32
KRT18 keratin 18, type I
LCN2 lipocalin 2
LEF1 lymphoid enhancer-binding factor 1
LGALS3 lectin, galactoside-binding, soluble, 3
MDK midkine (neurite growth-promoting factor 2)
MID1 midline 1
MMP12 matrix metallopeptidase 12
MMP9 matrix metallopeptidase 9
NAP1L1 nucleosome assembly protein 1-like 1
NELL2 NEL-like 2 (chicken)
NFE2L3 nuclear factor, erythroid 2-like 3
NLRP2 NLR family, pyrin domain containing 2
NQO1 NAD(P)H dehydrogenase, quinone 1
NTS neurotensin
OLFM4 olfactomedin 4
PHLDA1 pleckstrin homology-like domain, family A, member 1
PLK2 polo-like kinase 2
PPIF peptidylprolyl isomerase F
PRSS21 protease, serine, 21 (testisin)
RAP1GAP RAP1 GTPase activating protein
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B
SCGB1D2 secretoglobin, family 1D, member 2
SCGB2A2 secretoglobin, family 2A, member 2
SERPINB9 serpin peptidase inhibitor, clade B (ovalbumin), member 9
SMAD3 SMAD family member 3
SOX9 SRY (sex determining region Y)-box 9
STK32B serine/threonine kinase 32B
VEGFA vascular endothelial growth factor A