BRD-A22684332_Procaterol hydrochloride_VCAP_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

53 genes differentially expressed following the BRD-A22684332_Procaterol hydrochloride_VCAP_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AMD1 adenosylmethionine decarboxylase 1
AREG amphiregulin
ARMCX1 armadillo repeat containing, X-linked 1
CSRP1 cysteine and glycine-rich protein 1
CXCL9 chemokine (C-X-C motif) ligand 9
DUSP4 dual specificity phosphatase 4
DUSP5 dual specificity phosphatase 5
ERG v-ets avian erythroblastosis virus E26 oncogene homolog
ETS2 v-ets avian erythroblastosis virus E26 oncogene homolog 2
FHL1 four and a half LIM domains 1
GPM6B glycoprotein M6B
HSPA13 heat shock protein 70kDa family, member 13
IGKC immunoglobulin kappa constant
IKBKAP inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase complex-associated protein
IL2RG interleukin 2 receptor, gamma
JAG1 jagged 1
LRP4 low density lipoprotein receptor-related protein 4
LTF lactotransferrin
MAP1B microtubule-associated protein 1B
MAPKAPK2 mitogen-activated protein kinase-activated protein kinase 2
MAPT microtubule-associated protein tau
MTUS1 microtubule associated tumor suppressor 1
NKX3-1 NK3 homeobox 1
NUP98 nucleoporin 98kDa
OLFM4 olfactomedin 4
PCP4 Purkinje cell protein 4
PDE4B phosphodiesterase 4B, cAMP-specific
PLAT plasminogen activator, tissue
PRPF4 pre-mRNA processing factor 4
RAP1GAP2 RAP1 GTPase activating protein 2
SERPINB5 serpin peptidase inhibitor, clade B (ovalbumin), member 5
SIK1 salt-inducible kinase 1
SOX9 SRY (sex determining region Y)-box 9
SPEN spen family transcriptional repressor
TBX3 T-box 3
TFF1 trefoil factor 1
TGM4 transglutaminase 4
XBP1 X-box binding protein 1

decreased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
DEFB1 defensin, beta 1
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
HOXB2 homeobox B2
HOXB6 homeobox B6
KIF20A kinesin family member 20A
LAPTM4B lysosomal protein transmembrane 4 beta
MEIS1 Meis homeobox 1
MSLN mesothelin
MUC16 mucin 16, cell surface associated
RNASE1 ribonuclease, RNase A family, 1 (pancreatic)
RPL38 ribosomal protein L38
SCD stearoyl-CoA desaturase (delta-9-desaturase)
TXNIP thioredoxin interacting protein
VCAN versican
Funding