BRD-A22032524_AMLODIPINE BESYLATE_PC3_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

21 genes differentially expressed following the BRD-A22032524_AMLODIPINE BESYLATE_PC3_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ADGRG2 adhesion G protein-coupled receptor G2
AGR2 anterior gradient 2
BASP1 brain abundant, membrane attached signal protein 1
CLGN calmegin
CXCL8 chemokine (C-X-C motif) ligand 8
HMOX1 heme oxygenase 1
LCN2 lipocalin 2
PI3 peptidase inhibitor 3, skin-derived
PIR pirin (iron-binding nuclear protein)
S100P S100 calcium binding protein P
SLC4A4 solute carrier family 4 (sodium bicarbonate cotransporter), member 4
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
SQSTM1 sequestosome 1
TNFAIP6 tumor necrosis factor, alpha-induced protein 6

decreased expression

Symbol Name
ADGRL2 adhesion G protein-coupled receptor L2
EFEMP1 EGF containing fibulin-like extracellular matrix protein 1
IGFBP2 insulin-like growth factor binding protein 2, 36kDa
MX1 MX dynamin-like GTPase 1
PROM1 prominin 1
SFRP1 secreted frizzled-related protein 1
VTCN1 V-set domain containing T cell activation inhibitor 1